Results 51 to 60 of about 3,066,517 (203)

Alternative Splicing in Apicomplexan Parasites

mBio, 2019
Alternative splicing is a widespread, essential, and complex component of gene regulation. Apicomplexan parasites have long been recognized to produce alternatively spliced transcripts for some genes and can produce multiple protein products that are ...
Lee M. Yeoh, V. Vern Lee, Geoffrey I. McFadden, Stuart A. Ralph   +3 more
doaj   +1 more source

A Novel Prognostic Index Based on Alternative Splicing in Papillary Renal Cell Carcinoma

Frontiers in Genetics, 2020
BackgroundPapillary renal cell carcinoma (pRCC) is a heterogeneous multifocal or isolated tumor with an invasive phenotype. Previous studies presented that alternative splicing, as a crucial posttranscriptional regulator in gene expression, is associated
Zhipeng Wu, Jinhui Liu, Rui Sun, Dongming Chen, Kai Wang, Changchun Cao, Xianlin Xu   +6 more
doaj   +1 more source

Alternative splicing in addiction

Current Opinion in Genetics & Development
Addiction is a chronic and relapsing medical condition characterized by the compulsive use of drugs or alcohol despite harmful consequences. While transcriptional regulation has long been recognized for its role in addiction, recent genome-wide analyses have uncovered widespread alternative splicing changes that shift protein isoform diversity in ...
Akanksha Bhatnagar, Elizabeth A Heller
openaire   +2 more sources

Evolution of Alternative Splicing in Eudicots [PDF]

Frontiers in Plant Science, 2019
Alternative pre-mRNA splicing (AS) is prevalent in plants and is involved in many interactions between plants and environmental stresses. However, the patterns and underlying mechanisms of AS evolution in plants remain unclear. By analyzing the transcriptomes of four eudicot species, we revealed that the divergence of AS is largely due to the gains and
Ling, Zhihao, Brockmöller, Thomas, Baldwin, Ian T., Xu, Shuqing   +3 more
openaire   +5 more sources

Predicting the Impact of Alternative Splicing on Plant MADS Domain Protein Function [PDF]

, 2012
Several genome-wide studies demonstrated that alternative splicing (AS) significantly increases the transcriptome complexity in plants. However, the impact of AS on the functional diversity of proteins is difficult to assess using genome-wide approaches.
Morabito, G., Dijk, A.D.J., van, Severing, E.I., Busscher-Lange, J., Ham, R.C.H.J., van, Immink, G.H.   +5 more
core   +1 more source

Alternative Splicing: Emerging Roles in Anti-Aging Strategies

Biomolecules
Alternative splicing plays a fundamental role in gene expression and protein complexity. Aberrant splicing impairs cell homeostasis and is closely associated with aging and cellular senescence.
Lingyue Gao, Rong Jia
doaj   +1 more source

The role of alternative pre-mRNA splicing in cancer progression

Cancer Cell International, 2023
Alternative pre-mRNA splicing is a critical mechanism that generates multiple mRNA from a single gene, thereby increasing the diversity of the proteome. Recent research has highlighted the significance of specific splicing isoforms in cellular processes,
Sunkyung Choi, Namjoon Cho, Eun-Mi Kim, Kee K. Kim   +3 more
doaj   +1 more source

Editorial on alternative splicing and disease [PDF]

RNA Biology, 2010
(2010). Editorial on alternative splicing and disease. RNA Biology: Vol. 7, No. 4, pp. 388-389.
Barta Andrea, Schuemperli Daniel
openaire   +4 more sources

Alternative splicing and protein diversity: plants versus animals [PDF]

, 2019
Plants, unlike animals, exhibit a very high degree of plasticity in their growth and development and employ diverse strategies to cope with the variations during diurnal cycles and stressful conditions.
Khokhar, W., Reddy, A., Chaudhry, S., Wilson, C., Byrne, L., Syed, N., Jabre, I.   +6 more
core   +1 more source

An alternative definition of splicing

Theoretical Computer Science, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source