Results 21 to 30 of about 52,032 (257)

Predicting the Bioconcentration Factor in Fish from Molecular Structures

Toxics, 2022
The bioconcentration factor (BCF) is one of the metrics used to evaluate the potential of a substance to bioaccumulate into aquatic organisms. In this work, linear and non-linear regression QSARs were developed for the prediction of log BCF using ...
Linda Bertato, Nicola Chirico, Ester Papa   +2 more
doaj   +1 more source

Author Guide for Addressing Animal Methods Bias in Publishing

Advanced Science, 2023
There is growing recognition that animal methods bias, a preference for animal‐based methods where they are not necessary or where nonanimal‐based methods may already be suitable, can impact the likelihood or timeliness of a manuscript being accepted for
Catharine E. Krebs, Celean Camp, Helder Constantino, Lilas Courtot, Owen Kavanagh, Janine McCarthy, Melanie‐Jasmin Ort, Shaarika Sarasija, Emily R. Trunnell   +8 more
doaj   +1 more source

QSAR Models for the Prediction of Dietary Biomagnification Factor in Fish

Toxics, 2023
Xenobiotics released in the environment can be taken up by aquatic and terrestrial organisms and can accumulate at higher concentrations through the trophic chain.
Linda Bertato, Nicola Chirico, Ester Papa   +2 more
doaj   +1 more source

Predicting toxicity of chemicals: software beats animal testing

EFSA Journal, 2019
We created earlier a large machine‐readable database of 10,000 chemicals and 800,000 associated studies by natural language processing of the public parts of Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) registrations until
Thomas Hartung
doaj   +1 more source

First Organoid Intelligence (OI) workshop to form an OI community

Frontiers in Artificial Intelligence, 2023
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of power ...
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, Timothy D. Harris, Timothy D. Harris, Tzahi Cohen-Karni, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Alexander S. Szalay, Alexander S. Szalay, Fang Han, Donald J. Zack, Donald J. Zack, Donald J. Zack, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Daniel Tornero, Caroline Krall, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung, Thomas Hartung   +57 more
doaj   +1 more source

Effect of sub-chronic exposure to cigarette smoke, electronic cigarette and waterpipe on human lung epithelial barrier function

BMC Pulmonary Medicine, 2020
Background Taking into consideration a recent surge of a lung injury condition associated with electronic cigarette use, we devised an in vitro model of sub-chronic exposure of human bronchial epithelial cells (HBECs) in air-liquid interface, to ...
Baishakhi Ghosh, Hermes Reyes-Caballero, Sevcan Gül Akgün-Ölmez, Kristine Nishida, Lakshmana Chandrala, Lena Smirnova, Shyam Biswal, Venkataramana K. Sidhaye   +7 more
doaj   +1 more source

Give meaning to alternative methods to animal testing

ALTEX, 2019
n ...
Arti Ahluwalia, Anna Maria Bassi
openaire   +3 more sources

Automated measurement of the spontaneous tail coiling of zebrafish embryos as a sensitive behavior endpoint using a workflow in KNIME

MethodsX, 2021
Neuroactive substances are the largest group of chemicals detected in European surface waters. Mixtures of neuroactive substances occurring at low concentrations can induce adverse neurological effects in humans and organisms in the environment ...
Afolarin O. Ogungbemi, Elisabet Teixido, Riccardo Massei, Stefan Scholz, Eberhard Küster   +4 more
doaj   +1 more source

Giving meaning to alternative methods to animal testing

ALTEX, 2018
The 3 rd edition of the advanced theoretical-training course “ Giving meaning to alternative methods to animal testing ” was held in Genoa on July 6-7, 2017. The theoretical modules included talks by specialists from companies engaged in the field of advanced in vitro technologies, who offered participants the possibility to try out their technologies ...
Scanarotti C, Rovida C, Penco S, Vernqazza S, Tirendi S, Baldelli I, Ciliberti R, Bassi AM   +7 more
openaire   +3 more sources

Brain organoids and organoid intelligence from ethical, legal, and social points of view

Frontiers in Artificial Intelligence
Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain.
Thomas Hartung, Thomas Hartung, Itzy E. Morales Pantoja, Lena Smirnova   +3 more
doaj   +1 more source