Results 51 to 60 of about 843,251 (286)

IL-10 Dysregulation in Acute Mountain Sickness Revealed by Transcriptome Analysis

Frontiers in Immunology, 2017
Acute mountain sickness (AMS), which may progress to life-threatening high-altitude cerebral edema, is a major threat to millions of people who live in or travel to high altitude.
Bao Liu, Bao Liu, Bao Liu, Jian Chen, Jian Chen, Jian Chen, Long Zhang, Yixing Gao, Yixing Gao, Yixing Gao, Jianhua Cui, Erlong Zhang, Erlong Zhang, Erlong Zhang, Gang Xu, Gang Xu, Gang Xu, Yan Liang, Yu Liang, Jian Wang, Yuqi Gao, Yuqi Gao, Yuqi Gao   +22 more
doaj   +1 more source

Effect of High-Flow Oxygen on Exercise Performance in COPD Patients. Randomized Trial

Frontiers in Medicine, 2021
Background: High-flow oxygen therapy (HFOT) provides oxygen-enriched, humidified, and heated air at high flow rates via nasal cannula. It could be an alternative to low-flow oxygen therapy (LFOT) which is commonly used by patients with chronic ...
Konstantinos Bitos, Konstantinos Bitos, Konstantinos Bitos, Michael Furian, Michael Furian, Michael Furian, Laura Mayer, Laura Mayer, Laura Mayer, Simon R. Schneider, Simon R. Schneider, Simon R. Schneider, Simone Buenzli, Simone Buenzli, Simone Buenzli, Maamed Z. Mademilov, Maamed Z. Mademilov, Maamed Z. Mademilov, Ulan U. Sheraliev, Ulan U. Sheraliev, Ulan U. Sheraliev, Nuridin H. Marazhapov, Nuridin H. Marazhapov, Nuridin H. Marazhapov, Ainura K. Abdraeva, Ainura K. Abdraeva, Ainura K. Abdraeva, Shoira D. Aidaralieva, Shoira D. Aidaralieva, Shoira D. Aidaralieva, Aybermet M. Muratbekova, Aybermet M. Muratbekova, Aybermet M. Muratbekova, Talant M. Sooronbaev, Talant M. Sooronbaev, Talant M. Sooronbaev, Silvia Ulrich, Silvia Ulrich, Silvia Ulrich, Konrad E. Bloch, Konrad E. Bloch, Konrad E. Bloch   +41 more
doaj   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

High Altitude Illness [PDF]

Journal of the Royal Army Medical Corps, 2005
Introduction The aims of this article are to outline the physiology of high altitude, the treatment of altitude illness and to describe opportunities for further education in mountain medicine. Human difficulty with the rarefied air at high altitudes has been recognised since ancient times.
Davis, P, Pattinson, K, Mason, N, Richards, P, Hillebrandt, D   +4 more
openaire   +4 more sources

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Divergent Responses of Bacterial Communities to Permafrost Degradation and Their Associations With Carbon Across Vertical Profiles

Advanced Science, EarlyView.
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen, Yuzheng Gu, Ali Bahadur, Enyan Liu, Tonghua Wu, Xiaofan Zhu, Yuanqiang Zou, Hewei Liang, Peijie Wei, Linwei Wu, Qingbai Wu, Peizhi Yang, Hongyan Yu, Yunfeng Yang   +13 more
wiley   +1 more source

Hypoxic preacclimatization combining intermittent hypoxia exposure with physical exercise significantly promotes the tolerance to acute hypoxia

Frontiers in Physiology
Background: Both hypoxia exposure and physical exercise before ascending have been proved to promote high altitude acclimatization, whether the combination of these two methods can bring about a better effect remains uncertain.
Jiaxin Xie, Shenwei Xie, Zhifeng Zhong, Huaping Dong, Pei Huang, Simin Zhou, Huaijun Tian, Jijian Zhang, Yu Wu, Peng Li   +9 more
doaj   +1 more source

Effect of inhaled nitric oxide on oxygen-carrying capacity of red blood cells and hypoxia tolerance in mice

Di-san junyi daxue xuebao, 2019
Objective To study the effects of nitric oxide (NO) inhalation on oxygen-carrying capacity of red blood cells and hypoxia tolerance in mice. Methods Peripheral blood from 8-week-old male mice was exposed to nitrogen gas containing NO in an oxygenation ...
SU Wenting, CUI Yu, LI Xiaoxu, GUAN Libin   +3 more
doaj   +1 more source

Monitoring atmospheric pollutants with a heterodyne radiometer transmitter-receiver [PDF]

, 1973
The presence of selected atmospheric pollutants can be determined by transmitting an infrared beam of proper wavelength through the atmosphere, and detecting the reflections of the transmitted beam with a heterodyne radiometer transmitter-receiver using ...
Menzies, R. T.
core   +1 more source

Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window

Advanced Science, EarlyView.
Direct growth of sp2‐sp3 hybridized BN (HBN) on quartz, enabled by an h‐BN buffer, produces transparent and stable films up to 80 µm thick with high transmittance and strong neutron shielding, making HBN a promising candidate for space windows in long‐term lunar missions.
Dobin Kim, Geunpil Kim, Hwijoon Jeong, Sk Mujaffar Hossain, Satadeep Bhattacharjee, Minjae Isaac Kwon, Yeunjeong Lee, Chanhee Yang, Yeong Seok Ham, Taek‐Soo Kim, Hyowon Moon, Inkyu Park, Seung‐Cheol Lee, Jinhwan Kim, Jongbum Kim, Jaehyun Park   +15 more
wiley   +1 more source