Results 61 to 70 of about 456,779 (297)

Hypoxic preacclimatization combining intermittent hypoxia exposure with physical exercise significantly promotes the tolerance to acute hypoxia

Frontiers in Physiology
Background: Both hypoxia exposure and physical exercise before ascending have been proved to promote high altitude acclimatization, whether the combination of these two methods can bring about a better effect remains uncertain.
Jiaxin Xie, Shenwei Xie, Zhifeng Zhong, Huaping Dong, Pei Huang, Simin Zhou, Huaijun Tian, Jijian Zhang, Yu Wu, Peng Li   +9 more
doaj   +1 more source

Hump‐Shaped Relationship Between Microbial Carbon Use‐Efficiency and Soil Organic Carbon in Alpine Grasslands

Advanced Science, EarlyView.
On the Qinghai–Tibetan Plateau, microbial carbon use efficiency (CUE) peaks at intermediate soil organic carbon levels and declines thereafter. In carbon‐rich soils, the formation of stable mineral‐associated organic carbon is decoupled from microbial CUE.
Yuting Wang, Yongneng Wei, Gangsheng Wang, Yang Ruan, Ling Li, Xiang Liu, Yunfeng Yang, Qirong Shen, Ning Ling   +8 more
wiley   +1 more source

Altitude adaptation in Tibet caused by introgression of Denisovan-like DNA

Nature, 2014
As modern humans migrated out of Africa, they encountered many new environmental conditions, including greater temperature extremes, different pathogens and higher altitudes.
E. Huerta-Sánchez, Xin Jin, Asan, Zhuoma Bianba, B. Peter, N. Vinckenbosch, Yu Liang, X. Yi, Mingze He, M. Somel, Peixiang Ni, Bo Wang, X. Ou, Huasang, Jiangbai Luosang, Z. Cuo, G. Gao, Ye Yin, Wei Wang, Xiuqing Zhang, Xun Xu, Huanming Yang, Yingrui Li, Jian Wang, Jun Wang, R. Nielsen   +25 more
semanticscholar   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer

Cell Death and Disease
The role of epithelial membrane protein 1 (EMP1) in tumor microenvironment (TME) remodeling has not yet been elucidated. In addition, the biological function of EMP1 in triple-negative breast cancer (TNBC) is largely unclear.
Qi Wang, Dandan Li, Haixiu Ma, Zengyan Li, Juan Wu, Jinwan Qiao, Jun Liu, Jing Zhao, Ronghua Ma, Lin Tian, Lei Zhang, Jianye Yang, Jianing Wang, Shanshan Qin, Zhanhai Su   +14 more
doaj   +1 more source

The increase in hemoglobin concentration with altitude varies among human populations

Annals of the New York Academy of Sciences, 2019
Decreased oxygen availability at high altitude requires physiological adjustments allowing for adequate tissue oxygenation. One such mechanism is a slow increase in the hemoglobin concentration ([Hb]) resulting in elevated [Hb] in high‐altitude residents.
M. Gassmann, H. Mairbäurl, L. Livshits, S. Seide, Matthes Hackbusch, M. Malczyk, S. Kraut, Norina N. Gassmann, N. Weissmann, M. Muckenthaler   +9 more
semanticscholar   +1 more source

Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance

Advanced Science, EarlyView.
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang, Quan Li, Man Shi, Marcio F.A. Leite, Xinli Chen, Eiko E. Kuramae, Viviane Cordovez, Tingting Cao, Chenglei Zhu, Libin Zhou, Wenjuan Yu, Zhiyao Tang, Changhui Peng, Xinzhang Song   +13 more
wiley   +1 more source

Body Composition and Body Weight Changes at Different Altitude Levels: A Systematic Review and Meta-Analysis

Frontiers in Physiology, 2019
Changes in body composition and weight loss frequently occur when humans are exposed to hypoxic environments. The mechanisms thought to be responsible for these changes are increased energy expenditure resulting from increased basal metabolic rate and/or
T. Dünnwald, H. Gatterer, M. Faulhaber, M. Arvandi, W. Schobersberger   +4 more
semanticscholar   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Comparative transcriptomics of 3 high-altitude passerine birds and their low-altitude relatives

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance One potential limitation of the understanding of high-altitude adaptation is that most previous research focused on individual species, without taking into account the phylogenetic context in which similar genetic adaptations may have ...
Yan Hao, Ying Xiong, Yalin Cheng, G. Song, C. Jia, Yanhua Qu, F. Lei   +6 more
semanticscholar   +1 more source