Alveolar macrophages and the diagnosis of drowning [PDF]
In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema. When counting only the number of alveolar macrophages per alveolus without consideration of the alveolar size we found no relevant differences between the groups investigated ...
Betz, P. +3 more
openaire +5 more sources
Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis [PDF]
Pulmonary alveolar proteinosis (PAP) is a life-threatening, rare lung syndrome for which there is no cure and no approved therapies. PAP is a disease of lipid accumulation characterized by alveolar macrophage foam cell formation.
Elinor Lee +8 more
doaj +2 more sources
Alveolar presence of red blood cells correlates with alveolar macrophage iron levels in COPD
ackground: Pulmonary iron levels are increased in COPD patients. The number of iron positive alveolar macrophages correlates with increased COPD severity, which may be due to iron deposition from cigarette smoke or from red blood cells.
Dungwa, Josiah V +5 more
core +11 more sources
Tissue markers of alveolar macrophage accumulations in inhaled drug development
Alveolar macrophage accumulations in the lungs of rodents and dogs that have been exposed to inhaled new drug candidates is an important cause of attrition during preclinical drug development because it is very difficult to decide whether the ...
Hildebrand, Deon Dieter
core +6 more sources
Phagocytic properties of lung alveolar wall cells [PDF]
For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
core +1 more source
A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Francis, S. E. +63 more
core +1 more source
Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Griese, Matthias +5 more
core +1 more source
Lipid-laden alveolar macrophages and pH monitoring in gastroesophageal reflux-related respiratory symptoms [PDF]
Lipid-laden alveolar macrophages and pH monitoring have been used in the diagnosis of chronic aspiration in children with gastroesophageal reflux (GER).
Rosewich, Martin +7 more
core +1 more source
1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation. [PDF]
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Bose, Jens +9 more
core +1 more source
Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation [PDF]
The lung is, more than other solid organs, susceptible for ischemia reperfusion injury after orthotopic transplantation. Corticosteroids are known to potently suppress pro-inflammatory processes when given in the post-operative setting or during ...
Haitham Mutlak +29 more
core +2 more sources

