Results 31 to 40 of about 331,012 (291)

Production of Interferon by Alveolar Macrophages [PDF]

Journal of Bacteriology, 1966
Acton, JeanD. (Bowman Gray School of Medicine, Winston-Salem, N.C.),and Quentin N. Myrvik. Production of interferon by alveolar macrophages. J. Bacteriol.91:2300–2304. 1966.—Rabbit alveolar macrophages inoculated with parainfluenza-3 virus in vitro produce a viral inhibitor which possesses the properties of interferon.
J D, Acton, Q N, Myrvik
openaire   +2 more sources

Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity [PDF]

, 2011
Background: Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated ...
Bishop-Bailey, D, Mary C Sugden, David Bishop-Bailey, Bystrom, J, Holness Mark J., Sugden, MC, Mark J Holness, Holness, MJ, Jessica A. Wray, Wray, JA, Sugden, M C, Matthew L. Edin, Zeldin Darryl C., Zeldin, DC, Karen E Swales, Edin Matthew L., Edin, ML, Zeldin, D C, Sugden Mary C., Wray, J A, Gilroy Derek W., Swales Karen E., Darryl C Zeldin, Gilroy, DW, Derek W Gilroy, Karen E. Swales, Edin, M L, Mark J. Holness, Matthew L Edin, Derek W. Gilroy, Wray Jessica A., Gilroy, D W, Warner Timothy D., Jonas Bystrom, Warner, T D, Darryl C. Zeldin, Timothy D. Warner, Bishop-Bailey David, Bystrom Jonas, Holness, M J, Jessica A Wray, Swales, K E, Warner, TD, Timothy D Warner, Swales, KE, Mary C. Sugden   +45 more
core   +1 more source

The deadly dance of alveolar macrophages and influenza virus

European Respiratory Review
Influenza A virus (IAV) is one of the leading causes of respiratory infections. The lack of efficient anti-influenza therapeutics requires a better understanding of how IAV interacts with host cells.
Camille David, Charles Verney, Mustapha Si-Tahar, Antoine Guillon   +3 more
doaj   +1 more source

Pulmonary Alveolar Proteinosis in Setting of Inhaled Toxin Exposure and Chronic Substance Abuse

Case Reports in Pulmonology, 2018
Pulmonary alveolar proteinosis (PAP) is a rare lung disorder in which defects in alveolar macrophage maturation or function lead to the accumulation of proteinaceous surfactant in alveolar space, resulting in impaired gas exchange and hypoxemia.
Meirui Li, Salem Alowami, Miranda Schell, Clive Davis, Asghar Naqvi   +4 more
doaj   +1 more source

Alveolar macrophages lack CCR2 expression and do not migrate to CCL2

Journal of Inflammation, 2007
Background The recruitment of mononuclear cells has important implications for tissue inflammation. Previous studies demonstrated enhanced CCR1 and CCR5 expression and decreased CCR2 expression during in vitro monocyte to macrophage differentiation.
Hunter Melissa G, Lobb Jennifer M, Ali Naeem A, Opalek Judy M, Marsh Clay B   +4 more
doaj   +1 more source

Red Blood Cell-Derived Iron Alters Macrophage Function in COPD

Biomedicines, 2021
Lung macrophage iron levels are increased in COPD patients. Lung macrophage iron levels are thought to be increased by cigarette smoke, but the role of red blood cells (RBCs) as a source of iron has not been investigated.
James M. Baker, Molly Hammond, Josiah Dungwa, Rajesh Shah, Angeles Montero-Fernandez, Andrew Higham, Simon Lea, Dave Singh   +7 more
doaj   +1 more source

Peroxisome Proliferator-Activated Receptor-γ Regulates the Expression of Alveolar Macrophage Macrophage Colony- Stimulating Factor

, 2023
Macrophage CSF (M-CSF) regulates monocyte differentiation, activation, and foam cell formation. We have observed that it is elevated in human pulmonary alveolar proteinosis (PAP) and in the GMCSF knockout mouse, a murine model for PAP.
Culver, Daniel A., Thomassen, Mary Jane, Abraham, Susamma, Mosser, David M., Koloze, Mary T., NC DOCKS at East Carolina University, Farver, Carol F., Zhang, Xia, Bonfield, Tracey L.   +8 more
core  

Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers.

PLoS ONE, 2015
BackgroundHousehold air pollution in low income countries is an important cause of mortality from respiratory infection. We hypothesised that chronic smoke exposure is detrimental to alveolar macrophage function, causing failure of innate immunity.
Jamie Rylance, Chikondi Chimpini, Sean Semple, David G Russell, Malcolm J Jackson, Robert S Heyderman, Stephen B Gordon   +6 more
doaj   +1 more source

Immune modulation with sulfasalazine attenuates immunopathogenesis but enhances macrophage-mediated fungal clearance during Pneumocystis pneumonia. [PDF]

PLoS Pathogens, 2010
Although T cells are critical for host defense against respiratory fungal infections, they also contribute to the immunopathogenesis of Pneumocystis pneumonia (PcP).
Jing Wang, Francis Gigliotti, Samir P Bhagwat, Thaddeus C George, Terry W Wright   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source