Results 71 to 80 of about 1,184,873 (292)
Journal of Lipid Research, 2007 Patients with pulmonary alveolar proteinosis (PAP) display impaired surfactant clearance, foamy, lipid-filled alveolar macrophages, and increased cholesterol metabolites within the lung.
Mary Jane Thomassen +8 more
doaj +1 more source
Frontiers in Immunology, 2022 Intra-alveolar microvesicles (MVs) are important mediators of inter-cellular communication within the alveolar space, and are key components in the pathophysiology of lung inflammation such as acute respiratory distress syndrome (ARDS).
Sanooj Soni +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
The role of alveolar macrophages in viral respiratory infections and their therapeutic implications
Biochemistry and Biophysics ReportsAlveolar macrophages are pivotal components of the lung's innate immune defense against respiratory virus infections. Their multifaceted role spans from viral clearance to modulation of immune responses, making them essential players in shaping disease ...
Atefe Panahipoor Javaherdehi +4 more
doaj +1 more source
Isolation and Long-term Cultivation of Mouse Alveolar Macrophages
Bio-protocol, 2019 Alveolar macrophages (AM) are tissue-resident macrophages that colonize the lung around birth and can self-maintain long-term in an adult organism without contribution of monocytes.
C. Busch +4 more
semanticscholar +1 more source
Characterization of DEGs associated with DARs in mouse alveolar macrophages.
, 2023 (A and B) Identification of infection-associated differentially expressed genes in mouse alveolar macrophages. (A) Bar graph shows that a total of 3888 DEGs were identified, of which 2208 were upregulated and 1680 were downregulated.
Jun Zhang (48506) +17 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu +5 more
wiley +1 more source
Drug Delivery, 2019 The pulmonary delivery of locked nucleic acid containing antisense oligonucleotides (LNA-ASOs) is expected to be a novel therapeutic approach for lung diseases.
Yasunori Uemura, Katsuya Kobayashi
doaj +1 more source
Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection
Frontiers in Immunology, 2018 Pathogen persistence in the respiratory tract is an important preoccupation, and of particular relevance to infectious diseases such as tuberculosis. The equilibrium between elimination of pathogens and the magnitude of the host response is a sword of ...
B. Allard, A. Panariti, James G. Martin
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti +10 more
wiley +1 more source