Results 51 to 60 of about 1,184,873 (292)

Poractant alfa (Curosurf^®) increases phagocytosis of apoptotic neutrophils by alveolar macrophages in vivo

Respiratory Research, 2012
Background Clearance of apoptotic neutrophils in the lung is an essential process to limit inflammation, since they could become a pro-inflammatory stimulus themselves.
Willems Coen HMP, Urlichs Florian, Seidenspinner Silvia, Kunzmann Steffen, Speer Christian P, Kramer Boris W   +5 more
doaj   +1 more source

Alveolar macrophage-derived gVPLA2 promotes ventilator-induced lung injury via the cPLA2/PGE2 pathway

BMC Pulmonary Medicine, 2023
Background Ventilator-induced lung injury (VILI) is a clinical complication of mechanical ventilation observed in patients with acute respiratory distress syndrome.
Hanghang Han, Qiuwen Xie, Rongge Shao, Jinju Li, Xueke Du   +4 more
doaj   +1 more source

Phagocytic properties of lung alveolar wall cells [PDF]

, 1974
For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
core   +1 more source

Entry and elimination of marine mammal Brucella spp. by hooded seal (Cystophora cristata) alveolar macrophages in vitro. [PDF]

PLoS ONE, 2013
A high prevalence of Brucellapinnipedialis serology and bacteriology positive animals has been found in the Northeast Atlantic stock of hooded seal (Cystophoracristata); however no associated gross pathological changes have been identified. Marine mammal
Anett K Larsen, Ingebjørg H Nymo, Preben Boysen, Morten Tryland, Jacques Godfroid   +4 more
doaj   +1 more source

Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase [PDF]

, 2010
Heparanase is a heparan sulfate (HS) degrading endoglucuronidase that has been implicated in cell migration and inflammatory conditions. Here we used mice deficient of heparanase (Hpse−/−) to study the impact of heparanase on airway leukocytes.
Vlodavsky, Israel, Li, Jin-ping, Zcharia, Eyal, Pejler, Gunnar, Jia, Juan, Li, Jin-Ping,, Waern, Ida, Jia, Juan,, Wernersson, Sara, Sveriges lantbruksuniversitet., Waern, Ida,, Pejler, Gunnar,, Wernersson, Sara,   +12 more
core   +1 more source

Targeted PPARγ deficiency in alveolar macrophages disrupts surfactant catabolism

Journal of Lipid Research, 2010
Surfactant accumulates in alveolar macrophages of granulocyte-macrophage colony-stimulating factor (GM-CSF) knockout (KO) mice and pulmonary alveolar proteinosis (PAP) patients with a functional loss of GM-CSF resulting from neutralizing anti–GM-CSF ...
Anna D. Baker, Anagha Malur, Barbara P. Barna, Shobha Ghosh, Mani S. Kavuru, Achut G. Malur, Mary Jane Thomassen   +6 more
doaj   +1 more source

Lung resident alveolar macrophages regulate the timing of breast cancer metastasis

Cell
SUMMARY Breast disseminated cancer cells (DCCs) can remain dormant in the lungs for extended periods, but the mechanisms limiting their expansion are not well understood. Research indicates that tissue-resident alveolar macrophages suppress breast cancer
E. Dalla, Michael Papanicolaou, Matthew D. Park, Nicole D. Barth, Rui Hou, Deisy Segura-Villalobos, Luis Valencia-Salazar, Dan Sun, Alistair R. R. Forrest, M. Casanova-Acebes, David Entenberg, Miriam Merad, J. Aguirre-Ghiso   +12 more
semanticscholar   +1 more source

Assessment of the oxidative metabolism of calves’ bronchoalveolar cells: comparison between NBT and fluorimetric techniques

Arquivos do Instituto Biológico, 2018
: Evaluation of alveolar macrophage functions of cattle is an important tool in order to assess whether measures taken during the cattle husbandry can decrease the respiratory tract defense.
Bruna Artner, Angela Reck, Alessandra Mayer Coelho, Julio José Prediger, Desiree Vera Pontarolo, Heloisa Godoi Bertagnon   +5 more
doaj   +1 more source

The guardians of pulmonary harmony: alveolar macrophages orchestrating the symphony of lung inflammation and tissue homeostasis

European Respiratory Review
Recent breakthroughs in single-cell sequencing, advancements in cellular and tissue imaging techniques, innovations in cell lineage tracing, and insights into the epigenome collectively illuminate the enigmatic landscape of alveolar macrophages in the ...
L. Pervizaj-Oruqaj, M. R. Ferrero, U. Matt, S. Herold   +3 more
semanticscholar   +1 more source

Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates

BMC Immunology, 2012
Background Alveolar macrophages are one of the first lines of defence against invading pathogens and play a central role in modulating both the innate and acquired immune systems.
Groot-Kormelink Paul J, Fawcett Lindsay, Wright Paul D, Gosling Martin, Kent Toby C   +4 more
doaj   +1 more source