Results 41 to 50 of about 1,184,873 (292)
Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers
Respiratory Research, 2009 Background The small airway epithelium and alveolar macrophages are exposed to oxidants in cigarette smoke leading to epithelial dysfunction and macrophage activation. In this context, we asked: what is the transcriptome of oxidant-related genes in small
Hackett Neil R +5 more
doaj +1 more source
Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]
, 1983 Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
K James +7 more
core +1 more source
Vestnik MGTU, 2022 The goal of studying the mechanisms of action of cells that structure the immune system is to obtain additional data about the influence of immunomodulating peptides of natural origin on the possibility of regulating immune processes.
Kolberg N. A. +3 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
, 1975 The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
Kruse, F. +5 more
core +1 more source
Pathogenesis of chronic obstructive pulmonary disease [PDF]
, 2005 The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core +1 more source
Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation. [PDF]
PLoS ONE, 2013 Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract.
Mirjam Stahl +6 more
doaj +1 more source
Diversity of Macrophages in Lung Homeostasis and Diseases
Frontiers in Immunology, 2021 Lung macrophages play important roles in the maintenance of homeostasis, pathogen clearance and immune regulation. The different types of pulmonary macrophages and their roles in lung diseases have attracted attention in recent years.
Fei Hou +4 more
doaj +1 more source
Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism [PDF]
, 1989 The removal of neutrophils and their histotoxic contents from the inflamed site is a prerequisite for resolution of tissue injury, and a point at which factors critical to the pathogenesis of chronic inflammation may act.
Savill, John S +5 more
core +1 more source
Scientific Reports, 2017 Microbiota maintains host tissue homeostasis and influences tissue-resident macrophages. However, the mechanisms by which commensal bacteria in regulating the alveolar macrophages remain unclear. Here, by using an antibiotic-treated (Abt) mouse model, we
Min Cheng +9 more
doaj +1 more source
Tissue Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation.
American Journal of Respiratory Cell and Molecular Biology, 2020 Macrophage effector function is dynamic in nature and largely dependent upon not only the type of immunological challenge, but also the tissue-specific environment and developmental origin of a given macrophage population. Recent research has highlighted
P. S. Woods +8 more
semanticscholar +1 more source