Results 31 to 40 of about 1,184,873 (292)

Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease

Respiratory Research, 2020
Background Alveolar macrophages are professional phagocytes that remove microbial pathogens inhaled into the lung. The phagocytic ability is compromised in chronic obstructive pulmonary disease (COPD).
Atsushi Tanno, Naoya Fujino, Mitsuhiro Yamada, Hisatoshi Sugiura, Taizou Hirano, Rie Tanaka, Hirohito Sano, Satoshi Suzuki, Yoshinori Okada, Masakazu Ichinose   +9 more
doaj   +1 more source

The Role of Macrophages and Alveolar Epithelial Cells in the Development of ARDS

Inflammation, 2022
Acute lung injury (ALI) usually causes acute respiratory distress syndrome (ARDS), or even death in critical ill patients. Immune cell infiltration in inflamed lungs is an important hallmark of ARDS. Macrophages are a type of immune cell that participate
H. Tao, Younian Xu, Shi-Hai Zhang
semanticscholar   +1 more source

Lipid-laden alveolar macrophages and pH monitoring in gastroesophageal reflux-related respiratory symptoms [PDF]

, 2012
Lipid-laden alveolar macrophages and pH monitoring have been used in the diagnosis of chronic aspiration in children with gastroesophageal reflux (GER).
Rosewich, Martin, Rose, Markus A., H. J. Boehles, M. A. Rose, Kitz, Richard, M. Rosewich, Böhles, Hansjosef, R. Kitz   +7 more
core   +1 more source

Alveolar macrophages and the diagnosis of drowning [PDF]

, 1993
In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema.
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Betz, P.   +3 more
core   +1 more source

Paraquat promotes acute lung injury in rats by regulating alveolar macrophage polarization through glycolysis

Ecotoxicology and Environmental Safety, 2021
The present study investigates whether paraquat (PQ) regulates polarization of alveolar macrophages through glycolysis and promotes the occurrence of acute lung injury in rats.
Yan Zhang, Ding Yuan, Yi Li, Fang Yang, Linlin Hou, Yanwu Yu, Changhua Sun, Guoyu Duan, Cuicui Meng, Hongyi Yan, Dongxu Li, Yanxia Gao, Tongwen Sun, Changju Zhu   +13 more
doaj   +1 more source

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages [PDF]

, 2009
Background Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles.
Esmaeil Mortaz, Nijkamp, Frans P, Caldenhoven Eric, Caldenhoven, Eric, Kraneveld, Aletta D, Gert Folkerts, Sarir Hadi, Folkerts Gert, Nijkamp Frans P, Khalil Karimi, Kraneveld Aletta D, Karimi Khalil, Sarir, Hadi, Mortaz Esmaeil, Karimi, Khalil, Rahman Irfan, Folkerts, Gert, Frans P Nijkamp, Rahman, Irfan, Irfan Rahman, Eric Caldenhoven, Aletta D Kraneveld, Mortaz, Esmaeil, Hadi Sarir   +23 more
core   +1 more source

Alveolar macrophages lack CCR2 expression and do not migrate to CCL2

Journal of Inflammation, 2007
Background The recruitment of mononuclear cells has important implications for tissue inflammation. Previous studies demonstrated enhanced CCR1 and CCR5 expression and decreased CCR2 expression during in vitro monocyte to macrophage differentiation.
Hunter Melissa G, Lobb Jennifer M, Ali Naeem A, Opalek Judy M, Marsh Clay B   +4 more
doaj   +1 more source

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection

Nature Immunology, 2020
Despite the prevalence and clinical importance of influenza, its long-term effect on lung immunity is unclear. Here we describe that following viral clearance and clinical recovery, at 1 month after infection with influenza, mice are better protected ...
H. Aegerter, Justina Kulikauskaite, S. Crotta, H. Patel, G. Kelly, E. Hessel, M. Mack, S. Beinke, A. Wack   +8 more
semanticscholar   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Francis, S. E., Calogero Tulone, Read, R. C., Sheila E. Francis, Mitchell, T.J., Read Robert C., Benny Chain, Marriott, Helen M, Deretic, V., Dockrell, David H, Marriott, H.M., Francis, Sheila E, Dockrell, David H., Whyte, M.K.B., Martin A. Bewley, Mitchell Timothy J., Timothy J Mitchell, Whyte, Moira K B, Kroemer, G., Chain, B., Moira K. B. Whyte, Helen M Marriott, Sheila E Francis, Tulone Calogero, Robert C Read, Bewley, M.A., Dockrell, D.H., Whyte Moira K. B., Whyte, Moira K. B., Marriott Helen M., Read, Robert C., Marriott, H. M., Chain, Benny, Tulone, C., Read, R.C., Mitchell, Timothy J., Whyte, Moira K.B., David H. Dockrell, Mitchell, Timothy J, Francis Sheila E., David H Dockrell, Kroemer, Guido, Moira K B Whyte, Marriott, Helen M., Chain Benny, Mitchell, T. J., Timothy J. Mitchell, Bewley, Martin A, Dockrell, D. H., Read, Robert C, Tulone, Calogero, Francis, S.E., Robert C. Read, Dockrell David H., Bewley, Martin A., Martin A Bewley, Helen M. Marriott, Bewley, M. A., Dockrell, David, Bewley Martin A., Whyte, M. K. B., Guido Kroemer, Francis, Sheila E., Kroemer Guido   +63 more
core   +1 more source

Characterisation of lung macrophage subpopulations in COPD patients and controls

Scientific Reports, 2017
Lung macrophage subpopulations have been identified based on size. We investigated characteristics of small and large macrophages in the alveolar spaces and lung interstitium of COPD patients and controls.
Jennifer A. Dewhurst, Simon Lea, Elizabeth Hardaker, Josiah V. Dungwa, Arjun K. Ravi, Dave Singh   +5 more
doaj   +1 more source