Results 111 to 120 of about 9,882,917 (355)

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

BDNF expression mediates verbal learning and memory in women in a cohort enriched with risk for Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION This study examined whether sex differences in verbal learning and memory (VLM) are mediated by plasma brain‐derived neurotrophic factor (BDNF) expression.
Kyle J. Edmunds, Alyssa A. Pandos, Isabella Hoang, Gabriella M. Mamlouk, Alice Motovylyak, Sarah R. Lose, Sanjay Asthana, Matthew Stremlau, Sterling C. Johnson, Henriette vanPraag, Ozioma C. Okonkwo   +10 more
doaj   +1 more source

Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease

, 2022
Nesrine S. El-Mezayen, Rehab.A. Abd el Moneim, Safaa H. El‐Rewini   +2 more
openalex   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

A Metallo Pro‐Drug to Target Cu^II in the Context of Alzheimer's Disease [PDF]

, 2018
Amandine Conte‐Daban, Vinita Ambike, Régis Guillot, Nicolas Delsuc, Clotilde Policar, Christelle Hureau   +5 more
openalex   +1 more source

The role of NOTCH3 variants in Alzheimer's disease and subcortical vascular dementia in the Chinese population

, 2021
Lina Guo, Bin Jiao, Xinxin Liao, Xuewen Xiao, Weiwei Zhang, Zhenhua Yuan, Xixi Liu, Lu Zhou, Xin Wang, Yuan Zhu, Qijie Yang, Junling Wang, Beisha Tang, Lu Shen   +13 more
openalex   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Changes in Alzheimer's disease blood biomarkers in kidney failure before and after kidney transplant

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Alzheimer's disease (AD) blood biomarkers show promise for clinical diagnosis but their reliability in chronic kidney disease (CKD) is debated. This study investigates the impact of kidney transplant (KT) on AD biomarkers in CKD.
Anneka E. Blankenship, Lauren Yoksh, Paul J. Kueck, Jonathan D. Mahnken, Jill K. Morris, Aditi Gupta   +5 more
doaj   +1 more source

Longitudinal quantitative proton magnetic resonance spectroscopy of the hippocampus in Alzheimer's disease [PDF]

, 2002
Russell M. Dixon
openalex   +1 more source