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Cold Spring Harbor Perspectives in Biology, 2011 Alzheimer’s disease is a common health issue mostly found in elderly persons. An overview of the disease and a list of reliable Web-based information sources suitable for a general audience are ...
Watwood, Carol
core +3 more sources
Dissecting the human leptomeninges at single-cell resolution
Nature Communications, 2023 Emerging evidence shows that the meninges conduct essential immune surveillance and immune defense at the brain border, and the dysfunction of meningeal immunity contributes to aging and neurodegeneration.
Nicola A. Kearns +8 more
doaj +1 more source
npj Digital Medicine, 2023 Hand drawing, which requires multiple neural systems for planning and controlling sequential movements, is a useful cognitive test for older adults.
Shinya Tasaki +6 more
doaj +1 more source
2023 Alzheimer's disease facts and figures
Alzheimer's & Dementia, 2023 This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society.
semanticscholar +1 more source
Acta Neuropathologica Communications, 2021 Lewy bodies (LBs) and limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) are common in older persons and associated with cognitive impairment.
Sonal Agrawal +6 more
doaj +1 more source
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks
Nature Communications, 2022 Protein changes in a brain with Alzheimer’s are not often accompanied by transcriptional differences. Here, using a deep neural network that predicts protein abundance from mRNA expression, the authors track the early protein changes in Alzheimer’s ...
Shinya Tasaki +8 more
doaj +1 more source
Brain Sciences, 2021 The aim of the study was to examine potential cognitive, mood (depression and anxiety) and behavioral changes that may be related to the quarantine and the lockdown applied during the COVID-19 pandemic in Greek older adults with mild cognitive impairment
Marianna Tsatali +20 more
doaj +1 more source
Alzheimer’s Research & Therapy, 2022 Robust and accessible biomarkers that can capture the heterogeneity of Alzheimer’s disease and its diverse pathological processes are urgently needed. Here, we undertook an investigation of Alzheimer’s disease cerebrospinal fluid (CSF) and plasma from ...
Eric B. Dammer +7 more
doaj +1 more source
Biomedicine and Informatics Model of Alzheimer’s disease [PDF]
American Journal of Biochemistry and Biotechnology, 2007 In a perspective of biomedicine and informatics, the mechanism of Alzheimer's, senile amnesia, or other aging-associated and cognitive impairment related diseases involve four important informative processing procedures: propagation, consolidation, retrieval and cognition, In this study, we systematically model the four procedures based on published ...
Chang-Hua Zou, Kang Cheng
openaire +2 more sources
Survey Based Study: Classification of Patients with Alzheimer’s Disease
Iraqi Journal of Science, 2020 Neuroimaging is a description, whether in two-dimensions (2D) or three-dimensions (3D), of the structure and functions of the brain. Neuroimaging provides a valuable diagnostic tool, in which a limited approach is used to create images of the focal sensory system by medicine professionals.
Mohammed Sabbih Hamoud Al Tamimi +1 more
openaire +3 more sources