Results 11 to 20 of about 238,162 (269)

Alzheimer’s disease frequency peaks in the tenth decade and is lower afterwards

open access: yesActa Neuropathologica Communications, 2019
Age is the most robust risk factor for Alzheimer’s dementia, however there is little data on the relation of age to Alzheimer’s disease (AD) and other common neuropathologies that contribute to Alzheimer’s dementia.
Jose M. Farfel   +6 more
doaj   +1 more source

Assessment of Screening Approach in Early and Differential Alzheimer’s Disease Diagnosis

open access: yesAntioxidants, 2021
Background: Alzheimer’s disease (AD) is the leading cause of dementia in the elderly population. Currently, diagnosis is based on invasive and expensive techniques, so there is a growing need to look for other possible tests, as well as carry out ...
Laura Ferré-González   +5 more
doaj   +1 more source

Nuclear dynamics and stress responses in Alzheimer’s disease

open access: yesMolecular Neurodegeneration, 2021
In response to extracellular and intracellular stressors, the nucleus and nuclear compartments undergo distinct molecular changes to maintain cell homeostasis.
Artemis Iatrou   +2 more
doaj   +1 more source

ALZHEIMER’S DISEASE PROGNOSIS IS CAPTURED BY A DOWN-UPSIZED INCIDENCE POISSON DISTRIBUTION [PDF]

open access: yesAmerican Medical Journal, 2013
Alzeimer disease is a daunting nightmare to both the medical and families of the patients. Tireless efforts are made by the medical researchers to treat Alzheimer’s patients. The Alzhiemer patients’ data provides clues about its prognosis and they can be identifies when the data are analyzed and understood correctly.
openaire   +1 more source

Additional file 2: of The neuropathological diagnosis of Alzheimerâ s disease

open access: yes, 2019
Figure S2. Clinical Diagnoses of 227 Patients with a Pathologic Diagnosis of Pure AD. More than a third of pathologic AD cases on the Mayo Clinic Brain Bank from 2007 to 2016 were not expected to have AD. (PPTX 52 kb)
DeTure, Michael, Dickson, Dennis
openaire   +1 more source

Common age‐related neuropathologies and yearly variability in cognition

open access: yesAnnals of Clinical and Translational Neurology, 2019
Objective Cognitive variability is a potentially important source of heterogeneity in longitudinal cognitive profiles. We examined the extent to which common age‐related neuropathologies including Lewy bodies and Alzheimer’s disease (AD) contribute to ...
Lei Yu   +6 more
doaj   +1 more source

Additional file 3: of The neuropathological diagnosis of Alzheimerâ s disease

open access: yes, 2019
Figure S3. Pathologic Diagnoses in 626 Patients with Clinical Diagnosis of AD. The majority of clinical AD cases as observed in the Mayo Clinic Brain Bank from 2007 to 2016 were found to have co-pathologies. (PPTX 63 kb)
DeTure, Michael, Dickson, Dennis
openaire   +1 more source

A comparison between tau and amyloid-β cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease

open access: yesAlzheimer’s Research & Therapy, 2022
Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown.
Katherine W. Turk   +20 more
doaj   +1 more source

MOESM1 of Plasma lipoproteome in Alzheimerâ s disease: a proof-of-concept study

open access: yes, 2018
Additional file 1. Supplementary methods.
Li, Danni   +7 more
openaire   +1 more source

509 Understanding community engagement with research through a curated medical record-based database: A cross-sectional, single site study

open access: yesJournal of Clinical and Translational Science
Objectives/Goals: Since clinical trial participation is a key translational research initiative, the objectiveis to characterize research participants within a health system using electronic health record (EHR) data and evaluate how community-level ...
Chuan Ching Tsai   +5 more
doaj   +1 more source

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