Results 11 to 20 of about 277,634 (194)
Differential vulnerability of the dentate gyrus to tauopathies in dementias
Acta Neuropathologica Communications, 2023 The dentate gyrus (DG), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the Alzheimer’s type due to Alzheimer’s disease (DAT-AD), but less is known about the susceptibility ...
Allegra Kawles +14 more
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Assessment of Screening Approach in Early and Differential Alzheimer’s Disease Diagnosis
Antioxidants, 2021 Background: Alzheimer’s disease (AD) is the leading cause of dementia in the elderly population. Currently, diagnosis is based on invasive and expensive techniques, so there is a growing need to look for other possible tests, as well as carry out ...
Laura Ferré-González +5 more
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Alzheimer’s disease frequency peaks in the tenth decade and is lower afterwards
Acta Neuropathologica Communications, 2019 Age is the most robust risk factor for Alzheimer’s dementia, however there is little data on the relation of age to Alzheimer’s disease (AD) and other common neuropathologies that contribute to Alzheimer’s dementia.
Jose M. Farfel +6 more
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Epidemiology and Genetics of AlzheimerÂ’s Disease
Journal of Alzheimer’s Disease & Parkinsonism, 2015 Alzheimer’s disease (AD) is the most common form of dementia. It is a degenerative and incurable terminal disease. AD accounts for 75% of all forms of dementia all over the world. Its etiology is still unknown. Numerous risk factors of AD have already been discovered. In this paper, some preliminary results are presented.
Sery Omar +7 more
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Alzheimer’s disease and the fornix [PDF]
Frontiers in Aging Neuroscience, 2014 Alzheimer's disease (AD) is the most common form of neurodegenerative dementia. Researchers have long been focused on the cortical pathology of AD, since the most important pathologic features are the senile plaques found in the cortex, and the neurofibrillary tangles and neuronal loss that begin in the entorhinal cortex and the hippocampus.
Kenichi eOishi +3 more
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Nuclear dynamics and stress responses in Alzheimer’s disease
Molecular Neurodegeneration, 2021 In response to extracellular and intracellular stressors, the nucleus and nuclear compartments undergo distinct molecular changes to maintain cell homeostasis.
Artemis Iatrou +2 more
doaj +1 more source
Amyloidopathy in the Eye of Alzheimerâ²s Disease [PDF]
Journal of Addiction Research & Therapy, 2011 Alzheimer’s disease (AD) is a devastating neurodegenerative disease and the primary cause of dementia, with no cure available. The pathogenesis of AD is believed to be primarily driven by the accumulation of Aβ, a 4-kDa peptide generated from the amyloid-β precursor protein (APP) through proteolysis.
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Acta Neuropathologica Communications, 2022 Quantification of in vivo amyloid and tau PET imaging relationships with postmortem measurements are critical for validating the sensitivity and specificity imaging biomarkers across clinical phenotypes with Alzheimer disease neuropathologic change (ADNC)
Adam Martersteck +9 more
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Forecasting Disease Burden In Philippines: A Symbolic Regression Analysis [PDF]
arXiv, 2021 Burden of disease measures the impact of living with illness and injury and dying prematurely and it is increasing worldwide leading cause of death both global and national. This paper aimed to propose an index of diseases and evaluate a mathematical model to describe the number of burden of disease by cause in the Philippines from 1990 - 2016. Through
arxiv
Alzheimer’s Research & Therapy, 2022 Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown.
Katherine W. Turk +20 more
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