Results 31 to 40 of about 709,465 (344)

A comparison between tau and amyloid-β cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease

Alzheimer’s Research & Therapy, 2022
Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown.
Katherine W. Turk, Alexandra Geada, Victor E. Alvarez, Weiming Xia, Jonathan D. Cherry, Raymond Nicks, Gaoyuan Meng, Sarah Daley, Yorghos Tripodis, Bertrand R. Huber, Andrew E. Budson, Brigid Dwyer, Neil W. Kowall, Robert C. Cantu, Lee E. Goldstein, Douglas I. Katz, Robert A. Stern, Michael L. Alosco, Jesse Mez, Ann C. McKee, Thor D. Stein   +20 more
doaj   +1 more source

Obstructive sleep apnea severity affects amyloid burden in cognitively normal elderly a longitudinal study [PDF]

, 2018
Recent evidence suggests that Obstructive Sleep Apnea (OSA) may be a risk factor for developing Mild Cognitive Impairment and Alzheimer’s disease.
Bubu, Omonigho M., Romero Lafuente, Sergio, Sharma, Ram A., Varga, Andrew W.   +3 more
core   +2 more sources

Alzheimer’s disease and the fornix [PDF]

Frontiers in Aging Neuroscience, 2014
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia. Researchers have long been focused on the cortical pathology of AD, since the most important pathologic features are the senile plaques found in the cortex, and the neurofibrillary tangles and neuronal loss that begin in the entorhinal cortex and the hippocampus.
Kenichi eOishi, Constantine eLyketsos, Constantine eLyketsos, Constantine eLyketsos   +3 more
openaire   +4 more sources

Understanding Alzheimer’s Disease Knowledge in Low-Income, Richmond, VA Community Dwelling Older Adults [PDF]

, 2020
Background: Different populations of individuals demonstrate varying levels of Alzheimer’s disease (AD) knowledge, as well as commonly held misconceptions about the nature of the disease and its risk factors.
Inker, Jennifer, Rhodes, Ann, Richardson, Joann, Wilkerson, Taylor, Zanjani, Faika   +4 more
core   +1 more source

Adipobiology of the brain: From brain diabetes to adipose Alzheimer‘s disease

Adipobiology, 2015
Accumulating evidence suggests that brain-adipose tissue bidirectional communications might be promising intervention point for cardiometabolic and neurodegenerative diseases (1). Alzheimer‘s disease (AD) is a progressive and yet incurable disorder characterized by memory loss and cognitive ability deterioration. It is the most common form of dementia,
Luigi Aloe, Anton B. Tonchev, Alexander Maucher, Marco Fiore, Marin D. Zhelezov, George N. Chaldakov   +5 more
openaire   +2 more sources

Common age‐related neuropathologies and yearly variability in cognition

Annals of Clinical and Translational Neurology, 2019
Objective Cognitive variability is a potentially important source of heterogeneity in longitudinal cognitive profiles. We examined the extent to which common age‐related neuropathologies including Lewy bodies and Alzheimer’s disease (AD) contribute to ...
Lei Yu, Tianhao Wang, Robert S. Wilson, Sue Leurgans, Julie A. Schneider, David A. Bennett, Patricia A. Boyle   +6 more
doaj   +1 more source

Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer’s Coordinating Center Uniform Data Set

Alzheimer’s Research & Therapy, 2019
Background Longitudinal investigations are needed to improve understanding of the contributions of cerebral small vessel disease to the clinical manifestation of Alzheimer’s disease, particularly in the early disease stages.
Christian Puzo, Caroline Labriola, Michael A. Sugarman, Yorghos Tripodis, Brett Martin, Joseph N. Palmisano, Eric G. Steinberg, Thor D. Stein, Neil W. Kowall, Ann C. McKee, Jesse Mez, Ronald J. Killiany, Robert A. Stern, Michael L. Alosco   +13 more
doaj   +1 more source

Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology

Acta Neuropathologica Communications, 2022
Quantification of in vivo amyloid and tau PET imaging relationships with postmortem measurements are critical for validating the sensitivity and specificity imaging biomarkers across clinical phenotypes with Alzheimer disease neuropathologic change (ADNC)
Adam Martersteck, Ivan Ayala, Daniel T. Ohm, Callen Spencer, Christina Coventry, Sandra Weintraub, Eileen H. Bigio, M. -Marsel Mesulam, Changiz Geula, Emily Rogalski   +9 more
doaj   +1 more source

Inverse association between cancer and Alzheimer’s disease: results from the Framingham Heart Study [PDF]

, 2012
Objectives: To relate cancer since entry into the Framingham Heart Study with the risk of incident Alzheimer’s disease and to estimate the risk of incident cancer among participants with and without Alzheimer’s disease.
Au, Rhoda, Beiser, Alexa, Driver, Jane A, Kiel, Douglas P, Kreger, Bernard E, Kurth, Tobias, Lu, Kun Ping, Seshadri, Sudha, Splansky, Greta Lee, Wolf, Phillip A   +9 more
core   +1 more source

Multi-stage Biomarker Models for Progression Estimation in Alzheimer’s Disease [PDF]

, 2015
The estimation of disease progression in Alzheimer’s disease (AD) based on a vector of quantitative biomarkers is of high interest to clinicians, patients, and biomedical researchers alike.
Alejandro F. Frangi, Alexander Schmidt-Richberg, Christian Ledig, Daniel Rueckert, Helena Molina-Abril, null null, Ricardo Guerrero   +6 more
core   +1 more source