Results 11 to 20 of about 158,526 (239)
Network: Computation in Neural Systems, 2011 Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration. Eponymic diseases of the nervous system such as Alzheimer's, Parkinson's, and Huntington's diseases that were long characterized by mechanistic ignorance have yielded striking progress ...
Adam, Gazzaley, Scott A, Small
openaire +4 more sources
Neurology, 2021 > With each passing day, I lose a yesterday, > > And as yesterdays amass into yesteryears, > > Stacks of color photographs fade to gray.
openaire +2 more sources
Nature Reviews Disease Primers, 2021 Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic neurodegenerative disease that causes an amnestic cognitive impairment in its prototypical presentation and non-amnestic cognitive impairment in its less common variants.
David S. Knopman +7 more
openaire +2 more sources
eLife, 2020 To study the mechanisms by which the p.R47H variant of the microglia gene and Alzheimer’s disease (AD) risk factor TREM2 increases dementia risk, we created Trem2R47H KI rats.
Siqiang Ren +5 more
doaj +1 more source
NECESIDADES DEL CUIDADOR DEL ENFERMO DE ALZHEIMER TERMINAL.
Enfermería Global, 2005 La enfermedad de Alzheimer es la primera causa de demencia en la población occidental. Su carácter invalidante delega asistencia permanente desde los estadios moderados de la enfermedad por lo que la dependencia de cuidados constituye su principal ...
S. Sánchez Cánovas, R. Mears Baño
doaj +1 more source
Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?
Sakarya Tıp Dergisi, 2020 K vitamini yağda çözünen bir vitamin olup doğada filokinon (K1) ve menakinon (K2) formlarında bulunmaktadır. Menadion (K3) formu ise sentetik analog olarak kullanılmaktadır.
Aysegul Ugural, Aylin Ayaz
doaj +1 more source
Una escala para medir la aflicción del cuidador del paciente con Alzheimer
Voces desde el Trabajo Social, 2018 El objetivo de este estudio fue introducir el concepto de aflicción del cuidador o cuidadora del paciente con la enfermedad de Alzheimer y validar al español una escala breve para medir sus niveles y así evaluar la efectividad de la intervención ...
Jaime Alvelo Burgos +1 more
doaj +1 more source
Cells, 2020 Ca2+ is a ubiquitous second messenger that plays an essential role in physiological processes such as muscle contraction, neuronal secretion, and cell proliferation or differentiation.
Javier Alvarez +4 more
doaj +1 more source
Auditory Agnosia and Alzheimer's Disease: a Cohort Study
Revista Finlay, 2023 Foundation: recent evidence suggests that disorders caused by the onset of Alzheimer's disease can cause sound agnosia. Objective: to investigate whether patients with mild cognitive impairment and dementia as a symptom of Alzheimer's recognize ...
Manuel Conrado Ezcurdia Bárzaga +2 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source