Results 81 to 90 of about 461,295 (348)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

open access: yesActa Neuropathologica Communications, 2020
Recent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems.
Marta Perez-Rando   +5 more
doaj   +1 more source

Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine-v.4.0 [PDF]

open access: yes, 2011
There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I Baianu
core   +1 more source

Oral and Written Naming in Alzheimer's Disease: A Longitudinal Study [PDF]

open access: yes, 2018
This research was supported by Grant PSI2015-64174-P from the Spanish ...
Cuetos Vega, Fernando   +2 more
core   +2 more sources

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer   +3 more
wiley   +1 more source

Doe wel en zie niet om: alzheimer tast beslissen tot vrijgevigheid niet aan

open access: yesTijdschrift voor Gerontologie en Geriatrie, 2010
bespreking Bosch-Domènech, A., Nagel, R.,& Sánchez-Andrés, J. V. (2010). Prosocial capabilities in Alzheimer’s patients. Journal of Gerontology: Social Sciences, 65B, 119-128.
Han F. A. Diesfeldt
doaj   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt   +8 more
wiley   +1 more source

Larrea tridentata Extract Mitigates Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

open access: yesAntioxidants, 2019
Creosote bush (Larrea tridentata; LT) leaves extracts were tested for their potential efficacy to mitigate cellular oxidative stress on human SH-SY5Y cells. Here, the differential nuclear staining assay, a bioimager system, and flow cytometric protocols,
Karla Morán-Santibañez   +7 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Review of Postgraduate Dissertations on Alzheimer's Patients in Nursing Care

open access: yesYaşlı Sorunları Araştırma Dergisi
Increasingly, health problems have started to occur in the increasing elderly population. The physical and psychological problems that occur with aging have brought the search for new care and treatment methods to the agenda, and with the increase in ...
Fadime Toru
doaj   +1 more source

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