Results 1 to 10 of about 9,181,201 (335)

2023 Alzheimer's disease facts and figures

open access: yesAlzheimer's & Dementia, 2023
This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society.

semanticscholar   +1 more source

Modifiable psychosocial risk factors and delayed onset of dementia in older populations: analysis of two prospective US cohorts

open access: yesBMJ Open, 2022
Objective Preventing Alzheimer’s dementia (AD) fundamentally equates to delaying onset. Thus, we quantified associations of modifiable, psychosocial risk factors to years of delayed onset of dementia.Design Two prospective cohorts (n=2860) with negative ...
Robert S Wilson   +4 more
doaj   +1 more source

Lecanemab in Early Alzheimer's Disease.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND The accumulation of soluble and insoluble aggregated amyloid-beta (Aβ) may initiate or potentiate pathologic processes in Alzheimer's disease.
C. V. van Dyck   +18 more
semanticscholar   +1 more source

Discriminant Validity of the WAIS-R Digit Symbol Substitution Test in Subjective Cognitive Decline, Mild Cognitive Impairment (Amnestic Subtype) and Alzheimer’s Disease Dementia (ADD) in Greece

open access: yesBrain Sciences, 2021
Objective: The aim of the current study was to estimate the discriminant potential and validity of the Digit Symbol Substitution Test (DSST) of the WAIS-R in the Greek elderly population meeting criteria for subjective cognitive decline (SCD), mild ...
Marianna Tsatali   +8 more
doaj   +1 more source

Plasma microRNAs as potential biomarkers in early Alzheimer disease expression

open access: yesScientific Reports, 2022
The microRNAs (miRNAs) are potential biomarkers for complex pathologies due to their involvement in the regulation of several pathways. Alzheimer Disease (AD) requires new biomarkers in minimally invasive samples that allow an early diagnosis. The aim of
Carmen Peña-Bautista   +7 more
doaj   +1 more source

Emotional Function, Negative Thoughts about the Pandemic, and Adaptability Skills among Dementia Caregivers during the COVID-19 Pandemic

open access: yesBrain Sciences, 2022
Background: It can be easily inferred that dementia caregivers were severely affected by the general home confinement, or ‘lockdown’, due to their caregiving roles.
Evdokia Nikolaidou   +6 more
doaj   +1 more source

2021 Alzheimer's disease facts and figures

open access: yesAlzheimer's & Dementia, 2021
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society. The Special Report discusses the challenges
Anonymous
semanticscholar   +1 more source

Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells

open access: yesBiosensors, 2021
Presenilin (PS)/γ-secretase is an aspartyl protease that processes a wide range of transmembrane proteins such as the amyloid precursor protein (APP) and Notch1, playing essential roles in normal biological events and diseases.
Mei C. Q. Houser   +5 more
doaj   +1 more source

New insights into the genetic etiology of Alzheimer’s disease and related dementias

open access: yesNature Genetics, 2022
Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes.
C. Bellenguez   +402 more
semanticscholar   +1 more source

GPS driving: a digital biomarker for preclinical Alzheimer disease

open access: yesAlzheimer’s Research & Therapy, 2021
Background Alzheimer disease (AD) is the most common cause of dementia. Preclinical AD is the period during which early AD brain changes are present but cognitive symptoms have not yet manifest.
Sayeh Bayat   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy