Results 171 to 180 of about 317,693 (354)

Demonstration by Fluorescence Resonance Energy Transfer of a Close Association Between Activated MAP Kinase and Neurofibrillary Tangles: Implications for MAP Kinase Activation in Alzheimer Disease [PDF]

, 1999
Roger B. Knowles, Joanna Chin, Christian T. Ruff, Bradley T. Hyman   +3 more
openalex   +1 more source

Alzheimer's disease [PDF]

BMJ, 1994
M, Owen, M, Liddell, P, McGuffin
openaire   +2 more sources

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

Advanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang, Dajun Li, Xiao Ying Li, Weizhao Lu, Huini Ding, Chengyan Qi, Xuan Wang, Jing Shen, Yafei Chi, Tiantian Li, Michelle M. Dunk, Yu An, Hongmei Huang, Kang Yu, Weili Xu, Rong Xiao, Yuandi Xi   +16 more
wiley   +1 more source

The Role of Chronic Stress as a Trigger for the Alzheimer Disease Continuum

Frontiers in Aging Neuroscience, 2020
Marina Ávila-Villanueva, Jaime Gómez-Ramírez, Fernando Maestú, Fernando Maestú, César Venero, Jesús Ávila, Jesús Ávila, Miguel A. Fernández-Blázquez   +7 more
doaj   +1 more source

Stable intrachain and interchain complexes of neurofilament peptides: a putative link between Al3+ and Alzheimer disease.

, 1994
M. Hollósi, Ziyan Shen, A Perczel, Gerald D. Fasman   +3 more
openalex   +1 more source

Loss of Proteins Regulating Synaptic Plasticity in Normal Aging of the Human Brain and in Alzheimer Disease [PDF]

, 1999
Kimmo J. Hatanpaa, Krystyna R. Isaacs, Tomoaki Shirao, Daniel R. Brady, Stanley I. Rapoport   +4 more
openalex   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

Advanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou, Xi Xiong, Jialong Hou, Qi Duan, Yi Zheng, Tao Jiang, Jiani Huang, Haijun He, Jiaxue Xu, Keke Chen, Wenwen Wang, Jinlai Cai, Jingjing Qian, Huijun Chen, Weihong Song, XinShi Wang, Chenglong Xie   +16 more
wiley   +1 more source

Multipoint Oligogenic Analysis of Age-at-Onset Data with Applications to Alzheimer Disease Pedigrees [PDF]

, 1999
E. Warwick Daw, Simon Heath, Ellen M. Wijsman   +2 more
openalex   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Advanced glycation end products contribute to amyloidosis in Alzheimer disease.

, 1994
Michael P. Vitek, Koushik Bhattacharya, J M Glendening, Edward G. Stopa, Helen Vlassara, Richard Bucala, K Manogue, Anthony Cerami   +7 more
openalex   +1 more source