Results 181 to 190 of about 9,294,018 (384)

The Degeneration of the Human Mind: An Analysis of Alzheimer’s Disease, A Kuhnian Perspective [PDF]

, 2013
In 1906, a German physician, Dr. Alois Alzheimer, specifically identified a collection of brain cell abnormalities (and the formation of plaque in the brain) as a disease, which forever changed the way scientists view degenerative cognitive disorders ...
Ilg, Genevieve
core   +1 more source

Molecular cloning of amyloid cDNA derived from mRNA of the Alzheimer disease brain: coding and noncoding regions of the fetal precursor mRNA are expressed in the cortex.

, 1988
Sayeeda B. Zain, Mohammad Salim, W G Chou, E M Sajdel-Sulkowska, Ronald E. Majocha, Charles A. Marotta   +5 more
openalex   +1 more source

Modification of Metal Microelectrodes with Vertical Graphene Structure for Enhanced Electrochemical Detection of Dopamine

Advanced Materials Interfaces, EarlyView.
In this article, vertical graphene‐modified microelectrodes (VGMEs) are fabricated by modifying vertical graphene on different types of metal microelectrodes (Au, Ti, Ag, and W) for enhanced electrochemical detection of DA. Moreover, the sensing performance on dopamine concentrations is explored with different electrochemical methods, including EIS, CV,
Lukang Gao, Shuang Huang, Xiaotong Li, Zhengjie Liu, Xinshuo Huang, Yan Li, Hui‐jiuan Chen, Xudong Lin, Jing Liu, Xi Xie   +9 more
wiley   +1 more source

Amyloid precursor protein in peripheral granulocytes as a potential biomarker for Alzheimer’s disease

Bangladesh Journal of Pharmacology, 2016
The aim of this study was to assess the potential of amyloid precursor protein in peripheral granulocytes as a diagnostic biomarker for early detection of Alzheimer’s disease.
Xiaonan Wang, Xihai Li, Jie Yang, Ming Yu, Jinmei Wu   +4 more
doaj  

Increased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts. [PDF]

, 1991
Mark J. Adler, Carlos E. Coronel, Earl R. Shelton, J. Edwin Seegmiller, Nazneen N. Dewji   +4 more
openalex   +1 more source

Neuroinflammation in Alzheimer's disease

Lancet Neurology, 2015
M. Heneka, M. Carson, J. E. Khoury, G. Landreth, F. Brosseron, D. Feinstein, A. Jacobs, T. Wyss-Coray, T. Wyss-Coray, J. Vitorica, R. Ransohoff, K. Herrup, S. Frautschy, B. Finsen, Guy C. Brown, A. Verkhratsky, A. Verkhratsky, A. Verkhratsky, K. Yamanaka, J. Koistinaho, E. Latz, E. Latz, A. Halle, G. Petzold, T. Town, D. Morgan, M. Shinohara, V. Perry, C. Holmes, C. Holmes, N. Bazan, D. Brooks, S. Hunot, B. Joseph, N. Deigendesch, O. Garaschuk, E. Boddeke, C. Dinarello, J. Breitner, G. Cole, D. Golenbock, M. Kummer   +41 more
semanticscholar   +1 more source

A Flexible‐Substrate 5‐µm‐Diameter Needle Electrode: Minimizing Neuronal Death and Enabling Year‐Long Neural Recording

Advanced Materials Interfaces, EarlyView.
An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki, Koji Yamashita, Sayaki Shimizu, Kensei Sakamoto, Rika Numano, Kowa Koida, Takeshi Kawano   +6 more
wiley   +1 more source

Explainable Machine Learning Model for Alzheimer Detection Using Genetic Data: A Genome-Wide Association Study Approach

IEEE Access
Recent research has revealed that using machine learning systems for the analysis of genetic data could reliably detect Alzheimer’s disease. The interpretability of these models, however, has been a challenge, as they frequently provided little ...
Tarek Khater, Sam Ansari, Abbas Saad Alatrany, Haya Alaskar, Soliman Mahmoud, Ayad Turky, Hissam Tawfik, Eqab Almajali, Abir Hussain   +8 more
doaj   +1 more source

Exploring the Use of Mindfulness with Individuals Diagnosed with Alzheimer\u27s Disease [PDF]

, 2015
Alzheimer\u27s disease is one of the leading causes of death in the United States. This is a progressive disease with no cure. Are there interventions available to give individuals with Alzheimer\u27s disease hope?
Hemmesch, Gina L.
core   +1 more source

Glial fibrillary acidic protein immunohistochemical study of Alzheimer I & II astrogliosis in Wilson's disease

, 1988
Kaufmann Robert C., Z. R. Ye, Jie Fang, Jiajing Wu   +3 more
openalex   +1 more source