Results 121 to 130 of about 8,500 (184)

Exploring Bacteria from Extreme Environments in Chilean Patagonia for Antitrypanosomal Metabolites. [PDF]

ACS Omega
Albuquerque V, Lima JMG, Gonçalves MM, de Lima JAF, Kant R, Christodoulides M, Pimenta DC, Lago JHG, Santos C, Tempone AG.   +9 more
europepmc   +1 more source

Chemical genetics reveals Leishmania KKT2 and CRK9 kinase activity is required for cell cycle progression. [PDF]

PLoS Pathog
Carnielli JBT, Brannigan JA, Ramos PZ, Jones NG, Couñago RM, Sjö P, Lima APCA, Wilkinson AJ, Mottram JC.   +8 more
europepmc   +1 more source

In Vivo Efficacy and Biochemical Target Engagement of a Chromene-Based Inhibitor of Trypanosoma cruzi Lysyl-tRNA Synthetase. [PDF]

J Med Chem
Dos Santos TCF, de Lima Silva CC, Eufrásio AG, Tambascia C, De Sousa IL, Marchese L, Catelli MF, de Almeida LR, Costa Venancio GD, de Souza VB, Schenka AA, Rocco SA, Mercaldi GF, Cordeiro AT.   +13 more
europepmc   +1 more source

Extracellular Vesicle-Derived Spliced Leader RNA as a Minimally Invasive Molecular Biomarker for Leishmaniasis Detection. [PDF]

Trop Med Infect Dis
Sajjadi Oskouei M, Gonzalez JP, Mattei-Lopez DJ, Shoue DA, Koepfli C, McDowell MA.   +5 more
europepmc   +1 more source

Trypanocidal Effects of Polyprenylated Benzophenone Enriched Brazilian Red Propolis Extract and Its Isolated Constituent. [PDF]

Chem Biodivers
Oliveira ND, Pagotti MC, Paula LAL, Paixão MZ, Albino Dos Santos D, de Freitas RF, Ambrósio SR, Veneziani RCS, Bastos JK, Magalhães LG.   +9 more
europepmc   +1 more source

Exploring 6-Hydroxy-3-Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi. [PDF]

ChemMedChem
Pereira CN, Lara LDS, Lanera SDC, Souza TP, Pereira MCS, Delogu GL, Santos MSD, Matos MJ.   +7 more
europepmc   +1 more source

Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in <i>Trypanosoma cruzi</i> populations. [PDF]

Elife
Inchausti L, Bilbao L, Campo VA, Garat J, Sotelo-Silveira J, Rinaldi G, Howick VM, Duhagon MA, De Gaudenzi JG, Smircich P.   +9 more
europepmc   +1 more source

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Leishmania mexicana: Temperature sensitivity of isolated amastigotes and of amastigotes infecting macrophages in culture

Experimental Parasitology, 1983
Different temperature requirements for intracellular growth of Leishmania spp. may account for the predominantly peripheral or visceral localization of the parasites in the vertebrate host. We show here that Leishmania mexicana amazonensis, an agent of cutaneous disease, is growth restricted in vitro at 37.5 C and viable at 34 C.
D, Biegel, G, Topper, M, Rabinovitch
openaire   +2 more sources

Leishmania amazonensis:The Phagocytosis of Amastigotes by Macrophages

Experimental Parasitology, 1998
In the present study, we examine the cell biology of Leishmania amastigote uptake by mammalian cells and compare this process to the phagocytosis of IgG-opsonized erythrocytes. We report that many aspects of amastigote uptake into macrophages resemble classical receptor-mediated phagocytosis.
D C, Love, M, Mentink Kane, D M, Mosser
openaire   +2 more sources

Leishmania amazonensis: Acidic organelles in amastigotes

Experimental Parasitology, 1988
Leishmania amastigotes are intracellular protozoan parasites which exclusively invade cells of the macrophage series and multiply within phagolysosomes. Recent studies showed that intracellular and isolated amastigotes of L. amazonesis are killed by amino acid esters which appear to be trapped within as yet unidentified, possibly acidified, "lysosome ...
J C, Antoine, C, Jouanne, A, Ryter, J C, Benichou   +3 more
openaire   +2 more sources