Results 1 to 10 of about 11,452 (171)
The atypical dual-specificity protein phosphatase (DUSP)/kinatase of Leishmania infantum modulates infectivity, oxidative stress response and antimonial resistance. [PDF]
PLoS Neglected Tropical DiseasesDual-specificity protein phosphatases (DUSPs) are key modulators of mitogen-activated protein kinase (MAPK) signaling pathways that regulate cellular proliferation, differentiation, and stress adaptation.
Juliana Martins Ribeiro +9 more
doaj +2 more sources
Opšta Medicina, 2022 Introduction. The most common form of leishmaniasis is cutaneous leishmaniasis. It presents with cutaneous lesions of the unprotected parts of the skin which leave scars later on. The causative agents are protozoae from the Leishmania species , and there
Dacić Slavica D. +2 more
doaj +1 more source
The Characterization and Antileishmanial Evaluation on Leishmania Major with Chitosan/Zno Bio-Nanocomposite as Drug Delivery Systems [PDF]
Nanomedicine Research Journal, 2022 Background: Leishmaniasis is a global disease that poses a threat to human life and is associated with complications. Current medications have limitations due to serious side effects, costs and drug resistance.
Mohsen Mahmoudi +7 more
doaj +1 more source
Determination of the Effective Dose of Curcumin alone and in Combination with Antimicrobial Peptide CM11 on Promastigote Forms of Iranian Strain of L. major (MRHO / IR / 75 / ER) [PDF]
Archives of Razi Institute, 2019 Zoonotic cutaneous leishmaniasis t caused by Leishmania major is spread in focal areas of more than 90 countries in the tropics, subtropics, and southern Europe.
G. Aqeele +4 more
doaj +1 more source
Visceral Leishmaniasis, Northern Somalia, 2013–2019
Emerging Infectious Diseases, 2020 We identified visceral leishmaniasis caused by Leishmania donovani in a previously unknown focus in northern Somalia. Clinical and epidemiologic characteristics of 118 cases during 2013–2019 in Bosaso, the region’s commercial capital, have raised ...
Mikko K. Aalto +5 more
doaj +1 more source
Antiparasitic and cytotoxicity effects of 7-hydroxy-4′- methoxy isoflavone against Leishmania major [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Leishmaniasis caused by Leishmania spp. is observed in most parts of the world. Although, glucantime, a pentavalent antimony compound, and other synthetic drugs are broadly applied for leishmaniasis therapy; however, the use of these ...
Mahdi Aghaei +5 more
doaj +1 more source
Journal of Zoonotic Diseases, 2023 The disease Leishmaniasis is a neglected illness with two major forms clinically including cutaneous leishmaniasis and visceral leishmaniasis. From almost 100 endemic countries, an estimated one million additional records of leishmaniasis each year are
Basim Saleem Ahmed Al Sulivany +1 more
doaj +1 more source
Pathogens, 2022 Leishmaniasis is a protozoal vector-borne disease that affects both humans and animals. In the Mediterranean Basin, the primary reservoir hosts of Leishmania spp. are mainly rodents and canids.
Cyrine Bouabid +11 more
doaj +1 more source
Kinetic analysis of ex vivo human blood infection by Leishmania. [PDF]
PLoS Neglected Tropical Diseases, 2010 The leishmanioses, vector-borne diseases caused by the trypanosomatid protozoan Leishmania, are transmitted to susceptible mammals by infected phlebotomine sand flies that inoculate promastigotes into hemorrhagic pools created in host skin.
Inmaculada Moreno +4 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 The activity of five (1-5) abietane phenol derivatives against Leishmania infantum and Leishmania braziliensis was studied using promastigotes and axenic and intracellular amastigotes.
Inmaculada Ramírez-Macías +9 more
doaj +1 more source