Results 21 to 30 of about 11,452 (171)

Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG [PDF]

, 2004
Sand flies are the exclusive vectors of the protozoan parasite Leishmania, but the mechanism of transmission by fly bite has not been determined nor incorporated into experimental models of infection.
Bates, Paul A., Ilg, T., Nikolaev, Andrei V., Ferguson, Michael AJ, Andrei V. Nikolaev, Matthew E. Rogers, Ilg, Thomas, Ferguson, Michael A. J.; id_orcid, Ferguson, M. A. J., Rogers, Matthew E., Ferguson, Michael A J, Paul A. Bates, Michael A. J. Ferguson, Rogers, Matthew E, Thomas Ilg, Bates, Paul, Nikolaev, Andrei V, Bates, Paul A, Nikolaev, A. V.   +18 more
core   +1 more source

In vitro Anti-Leishmanial Activities of Methanol Extract of Brucea antidysenterica J.F. Mill Seeds and Its Solvent Fractions

Journal of Experimental Pharmacology, 2023
Tasisa Ketema,1 Markos Tadele,2 Zewdie Gebrie,1 Eyasu Makonnen,1,3 Asrat Hailu,3,4 Solomon M Abay1 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia; 2Animal ...
Ketema T, Tadele M, Gebrie Z, Makonnen E, Hailu A, Abay SM   +5 more
doaj  

Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania [PDF]

, 2009
Background Leishmania parasites must overcome several barriers to achieve transmission by their sand fly vectors. One of the earliest threats is exposure to enzymes during blood meal digestion.
Rod J Dillon, Dillon, Rod J, Hector Diaz-Albiter, Sant'Anna, Mauricio R.V., Sant'anna, Mauricio Rv, Paul A Bates, Diaz-Albiter Hector, Dillon, Rod, Dillon Rod J, Diaz-Albiter, Hector, Mauricio RV Sant'Anna, Bates, Paul, Mubaraki, Murad, Sant'Anna Mauricio RV, Murad Mubaraki, Bates, Paul A, Bates Paul A, Mubaraki Murad   +17 more
core   +5 more sources

Effects of hydroalcoholic extract of Glycyrrhiza glabra and glycyrrhizic acid on promastigote and amastigote of Leishmania major (MRHO/IR/75/ER)

Journal of Medicinal Plants, 2020
Background: Cutaneous leishmaniasis by different species of Leishmania. Pentavalen antimonials as a first line drug for treatment of cutaneous leishmaniasis have several limitations and side effects. Natural products are more considered due to their less
Shima Sheikhi, Ali Khamesipour, Tayebeh Radjabian, Zahra Mojallal Tabatabaei, Tooba Ghazanfari   +4 more
doaj  

The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo

Memorias do Instituto Oswaldo Cruz, 2015
Despite recent advances in the treatment of some forms of leishmaniasis, the available drugs are still far from ideal due to inefficacy, parasite resistance, toxicity and cost.
Sergio Sifontes-Rodríguez, Lianet Monzote-Fidalgo, Nilo Castañedo-Cancio, Ana Margarita Montalvo-Álvarez, Yamilé López-Hernández, Niurka Mollineda Diogo, Juan Francisco Infante-Bourzac, Oliver Pérez-Martín, Alfredo Meneses-Marcel, José Antonio Escario García-Trevijano, Miguel Ángel Cabrera-Pérez   +10 more
doaj   +1 more source

Examining the Relationship of Clinical and Laboratory Parameters With Infectiousness to Phlebotomus perniciosus and Its Potential Infectivity in Dogs With Overt Clinical Leishmaniasis

Frontiers in Veterinary Science, 2021
Infected dogs are considered the main domestic animal reservoirs for Leishmania infantum parasite. Infectiousness to competent phlebotomine vectors has been associated with many factors, the main being the severity of the disease exhibited by infected ...
Manuela Gizzarelli, Antonio Bosco, Valentina Foglia Manzillo, Gioia Bongiorno, Riccardo Bianchi, Daniela Giaquinto, Nour El Houda Ben Fayala, Marie Varloud, Alessia Crippa, Luigi Gradoni, Giuseppe Cringoli, Maria Paola Maurelli, Laura Rinaldi, Gaetano Oliva   +13 more
doaj   +1 more source

Antileashmanial activity of Artemisia sieberi essential oil against Leishmania infantum in vitro [PDF]

Advanced Herbal Medicine, 2017
Background and aims: VL (Viseral Leishmaniosis) the second- most dreaded parasitic disease after malaria is currently endemic in 88 countries. Artemisia sieberi is native medicinal plants in Iran and their effects are scientifically proven to be ...
elham moghaddas, Mohaddeseh Abouhosseini Tabari, Mohammad Reza Youssefi, Mohammad Amin Ebrahimi, Nilofar Nabavi Mousavi, ali naseri   +5 more
doaj  

Antigenic differences among Leishmania amazonensis isolates and their relationship with distinct clinical forms of the disease

Memorias do Instituto Oswaldo Cruz, 1992
Immunoblot analysis was used to investigate antigenic differences among clinical isolates of Leishmania amazonensis and their role in the etiology of the diseases. Western blots of promastigote homogenates were analyzed with either monoclonal antibodies (
Leonor L. Leon, Gerzia M. C. Machado, Aldina Barral, Luiz E. de Carvalho-Paes, Gabriel Grimaldi Júnior   +4 more
doaj   +1 more source

Gelatin Zymography of Major Proteases in Exosomes of Leishmania major Promastigotes

Iranian Journal of Parasitology, 2023
Background: Enzymatic digestion of extra cellular matrix proteins by proteinases of   Leishmania promastigotes is a complex process. Hence, studies on functional proteomics of these enzymes can help select these enzymes as possible vaccine candidates or
Akram Azambakhtiar, Sedigheh Nabian, Mehdi Mohebali, Mohammad Taheri, Ramin Mazaheri Nezhad Fard   +4 more
doaj   +1 more source

Leishmanicidal Activity and Cytotoxicity of Thymus kotschyanus Hydroalcoholic Extract: an In Vitro Assessment [PDF]

Research Journal of Pharmacognosy
Background and objectives: Current leishmaniasis treatment shows limitations such as side effects, low efficacy, and resistance. Thymus species are well-known as medicinal plants.
Maryam Nematollahi, Amir Mehdi Taleb, Seyyed Javad Seyyed-Tabaei, Nayebali Ahmadi*   +3 more
doaj   +1 more source