Results 21 to 30 of about 11,689 (228)
Journal of Experimental Pharmacology, 2023 Tasisa Ketema,1 Markos Tadele,2 Zewdie Gebrie,1 Eyasu Makonnen,1,3 Asrat Hailu,3,4 Solomon M Abay1 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia; 2Animal ...
Ketema T +5 more
doaj
Journal of Medicinal Plants, 2020 Background: Cutaneous leishmaniasis by different species of Leishmania. Pentavalen antimonials as a first line drug for treatment of cutaneous leishmaniasis have several limitations and side effects. Natural products are more considered due to their less
Shima Sheikhi +4 more
doaj
, 2022 In vitro cytotoxicity effect of pentamidine and LASSBio-1491 against spleen cells and promastigote forms of L. major.
Gisele Barbosa (12800027) +9 more
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The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo
Memorias do Instituto Oswaldo Cruz, 2015 Despite recent advances in the treatment of some forms of leishmaniasis, the available drugs are still far from ideal due to inefficacy, parasite resistance, toxicity and cost.
Sergio Sifontes-Rodríguez +10 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 Infected dogs are considered the main domestic animal reservoirs for Leishmania infantum parasite. Infectiousness to competent phlebotomine vectors has been associated with many factors, the main being the severity of the disease exhibited by infected ...
Manuela Gizzarelli +13 more
doaj +1 more source
Proteome Profiling of Leishmania Infantum Promastigotes
Journal of Eukaryotic Microbiology, 2011 ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J. +2 more
openaire +3 more sources
Comparison of flux distributions between the promastigote and amastigote scenarios.
, 2015 A) Scatter plot showing the variation of fluxes from the promastigote to amastigote forms B) Bar plot showing differences between overflow metabolism in the two developmental stages of L.
Ram Rup Sarkar (194707) +2 more
core +1 more source
Antileashmanial activity of Artemisia sieberi essential oil against Leishmania infantum in vitro [PDF]
Advanced Herbal Medicine, 2017 Background and aims: VL (Viseral Leishmaniosis) the second- most dreaded parasitic disease after malaria is currently endemic in 88 countries. Artemisia sieberi is native medicinal plants in Iran and their effects are scientifically proven to be ...
elham moghaddas +5 more
doaj
Memorias do Instituto Oswaldo Cruz, 1992 Immunoblot analysis was used to investigate antigenic differences among clinical isolates of Leishmania amazonensis and their role in the etiology of the diseases. Western blots of promastigote homogenates were analyzed with either monoclonal antibodies (
Leonor L. Leon +4 more
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Gelatin Zymography of Major Proteases in Exosomes of Leishmania major Promastigotes
Iranian Journal of Parasitology, 2023 Background: Enzymatic digestion of extra cellular matrix proteins by proteinases of Leishmania promastigotes is a complex process. Hence, studies on functional proteomics of these enzymes can help select these enzymes as possible vaccine candidates or
Akram Azambakhtiar +4 more
doaj +1 more source