Results 41 to 50 of about 537 (160)

Two new species of Amanita sect. Phalloideae from Africa, one of which is devoid of amatoxins and phallotoxins [PDF]

open access: yesMycoKeys, 2019
Two new species of Amanita sect. Phalloideae are described from tropical Africa (incl. Madagascar) based on both morphological and molecular (DNA sequence) data. Amanita bweyeyensis sp. nov.
André Fraiture   +5 more
doaj   +3 more sources

Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists

open access: yesArchiv der Pharmazie, Volume 359, Issue 6, June 2026.
Despite its long tradition in the treatment of liver‐related ailments, the precise mode of action of the milk thistle fruit extract remains vague. Here we identified liver X receptor as a molecular target of silymarin, a mixture of bioactive compounds from milk thistle extract, and its major flavanonol lignan components, which account for their anti ...
Nils C. Bandomir   +3 more
wiley   +1 more source

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range

open access: yesNew Phytologist, Volume 250, Issue 3, Page 1863-1883, May 2026.
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Grant R. Nickles   +39 more
wiley   +1 more source

Convergence and parallelism in the evolution of plant metabolism

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 4, Page 1013-1031, April 2026.
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa   +4 more
wiley   +1 more source

Diphenylphosphinylhydroxylamine (DPPH) Affords Late‐Stage S‐imination to access free‐NH Sulfilimines and Sulfoximines

open access: yesAngewandte Chemie, Volume 136, Issue 13, March 22, 2024.
Metal‐free, and high‐yielding sulfur‐imination using O‐(diphenylphosphinyl)hydroxyl amine to access sulfilimine salts and free‐NH sulfoximines has been reported. Its generality was evidenced using a broad substrate scope along with late‐stage functionalization of complex, biologically relevant substrates including a notorious amatoxin.
Shanal Gunasekera   +5 more
wiley   +2 more sources

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana   +4 more
wiley   +1 more source

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai   +8 more
wiley   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

open access: yesFood Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah   +1 more
wiley   +1 more source

Mechanisms and aetiology‐dependent treatment of acute liver failure

open access: yesLiver International, Volume 45, Issue 3, March 2025.
Abstract This review compiles the mechanisms of acute liver failure (ALF) as well as the current and potential therapeutic approaches, including aetiology‐specific treatment, and the issues encountered with such approaches. On a cellular level, ALF is characterized by massive hepatocyte death due to different types of cellular demise.
Peter Lemmer   +4 more
wiley   +1 more source

A Rare Case of Amatoxin Poisoning in the State of Texas [PDF]

open access: yesCase Reports in Gastroenterology, 2012
Ingestion of mushrooms from the genus Amanita can present detrimental consequences to the human body. The mushroom is frequently found in the coastal Pacific Northwest, Pennsylvania, New Jersey, and Ohio. Amanitin, one of the two distinct toxins isolated from the Amanita mushroom, is responsible for the majority of symptoms and signs seen with mushroom
Wei-Chung Chen   +3 more
openaire   +3 more sources

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