Results 51 to 60 of about 537 (160)

Food Safety in Developing Countries: Common Foodborne and Waterborne Illnesses, Regulations, Organizational Structure, and Challenges of Food Safety in the Context of Nepal

open access: yesFood Frontiers, Volume 6, Issue 1, Page 86-123, January 2025.
Food safety presents a global challenge, contributing to 600 million cases of foodborne diseases and 420,000 fatalities annually worldwide. A multisectoral One Health approach involving collaboration among government agencies, food industry stakeholders, consumers, and civil society organizations is imperative to enhance food safety in developing ...
Deepak Subedi   +3 more
wiley   +1 more source

Hepatotoxicity from ingestion of wild mushrooms of the genus Amanita section Phalloideae collected in Mexico City: two case reports

open access: yesAnnals of Hepatology, 2011
We present two cases of acute liver injury resulting from consumption of wild mushrooms. The first case was a male who developed acute hepatitis after ingestion of diverse mushrooms including Amanita species.
Jorge Méndez-Navarro   +11 more
doaj   +1 more source

Morchella esculenta (L.) Pers. Wild of the Province of Taza, Morocco: Toxicity Assessment in In Vitro and In Vivo Models, Antioxidant Activities and Correlation With the Chemical Composition of Aqueous and Organic Extracts

open access: yesBiochemistry Research International, Volume 2025, Issue 1, 2025.
Mushrooms are a source of nutrients and bioactive substances. This work, carried out for the first time, aims to evaluate in vitro and in vivo toxicity and antioxidant potential of the wild edible mushroom from the province of Taza, Morocco: Morchella esculenta (L.) Pers., the extraction is carried out using two methods: aqueous and organic.
Asmae Mahtal   +5 more
wiley   +1 more source

VISTA‐targeted antibody‐drug conjugates exhibit potent antitumor effects on malignant pleural mesothelioma

open access: yesMedComm – Oncology, Volume 3, Issue 2, June 2024.
In this study, moderate to high V‐domain immunoglobulin T‐cell activation suppressor (VISTA) expression levels were observed in most malignant pleural mesothelioma (MPM) clinical tumor samples. We generated two novel VISTA‐targeted antibody‐drug conjugates by conjugating anti‐VISTA mAbs with the potent cytotoxic drug monomethyl auristatin E, which ...
Jingyue Kang   +7 more
wiley   +1 more source

Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases—A comprehensive narrative review

open access: yesFood Science &Nutrition, Volume 12, Issue 5, Page 3097-3111, May 2024.
A thorough examination of the substantiating evidence supporting its use as an adjunctive therapy for individuals grappling with liver‐related conditions. Abstract Liver diseases, encompassing conditions such as cirrhosis, present a substantial global health challenge with diverse etiologies, including viral infections, alcohol consumption, and non ...
Hafiza Madiha Jaffar   +4 more
wiley   +1 more source

A New Conjugation Method Used for the Development of an Immunoassay for the Detection of Amanitin, a Deadly Mushroom Toxin

open access: yesToxins, 2018
One of the deadliest mushrooms is the death cap mushroom, Amanita phalloides. The most toxic constituent is α-amanitin, a bicyclic octapeptide, which damages the liver and kidneys.
Candace S. Bever   +4 more
doaj   +1 more source

5‐Hydroxypyrroloindoline Affords Tryptathionine and 2,2′‐bis‐Indole Peptide Staples: Application to Melanotan‐II

open access: yesChemistry – A European Journal, Volume 30, Issue 19, April 2, 2024.
Optionality for Indole‐based Peptide Stapling: hydroxypyrroloindoline, used regularly in reaction with cysteine to form a tryptathionine (Ttn) staple is found to react competitively with an indole to form a 2’2’‐bis‐indole tether (BITe). Judicious choice of protecting groups provides for chemoselectivity for optionality in terms of which staple is ...
Mihajlo Todorovic   +9 more
wiley   +1 more source

The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes

open access: yesIMA Fungus, 2018
The biosynthetic pathway for amanitins and related cyclic peptides in deadly Amanita (Amanitaceae) mushrooms represents the first known ribosomal cyclic peptide pathway in the Fungi.
Hong Luo   +6 more
doaj   +1 more source

Amatoxins in edible mushrooms [PDF]

open access: yesFEBS Letters, 1976
Faulstich, H., Cochet-Meilhac, M.
openaire   +3 more sources

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