Results 51 to 60 of about 5,969 (169)

Guía clínica para el manejo de la faringoamigdalitis aguda del adulto [PDF]

, 2015
La faringoamigdalitis aguda (FAA) en el adulto es una de las enfermedades infecciosas más comunes en la consulta del médico de familia. La etiología más frecuente es viral.
Alós Cortés, Juan-Ignacio, Boleda Relats, Xavier, Bárcena Caamaño, Mario, Cañada Merino, José Luis, Cots Yago, Josep Maria, Gómez Gabaldón, Niceto, Llor Vila, Carles, Mendoza Barbero, Ana, Vilaseca González, Isabel   +8 more
core   +1 more source

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza, Roberto Giugliani, Debra S. Regier, Jeanine Jarnes   +3 more
wiley   +1 more source

Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

Frontiers in Pharmacology, 2019
Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS.
Alexandra Bouscary, Alexandra Bouscary, Cyril Quessada, Cyril Quessada, Althéa Mosbach, Althéa Mosbach, Noëlle Callizot, Michael Spedding, Jean-Philippe Loeffler, Jean-Philippe Loeffler, Alexandre Henriques, Alexandre Henriques, Alexandre Henriques   +12 more
doaj   +1 more source

Penerapan Algorithma K-mean Untuk Clustering Data Obat Pada Puskesmas Rumbai [PDF]

, 2016
Melalui program jaminan kesehatan pemerintah berupaya terus menjamin kesehatan bagi masyarakat melalui puskesmas puskesmas atau balai pengobatan. Salah satu komponen yang sangat penting pada puskesmas maupun balai pengobatan adalah masalah ketersediaan ...
Fajrizal, F. (Fajrizal), Taslim, T. (Taslim)   +1 more
core  

Anthelmintic Effect of Chitosan‐Encapsulated Bromelain on Gastrointestinal Nematodes in Naturally Infected Goats in Kenya

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
The emergence of anthelmintic resistance calls for the development of alternatives, including medicinal plant extracts. The present study was aimed at assessing the efficacy of chitosan‐encapsulated bromelain (EB) as an oral solution drug against GIN in goats.
Ahmota Romain Daïba, Issa Youssouf Adoum, Maina Ngotho, John Maina Kagira, Naomi Maina, Bernard Marchand   +5 more
wiley   +1 more source

Respiratory Failure Associated With Mutations in the RYR1 Gene: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT A novel RYR1 mutation (c.C5701T:p.Q1901X) was identified in a 51‐year‐old female presenting with acute respiratory failure as the primary manifestation of congenital myopathy. This case expands the genotype–phenotype spectrum of RYR1‐related myopathies and demonstrates that multidisciplinary intervention—including ventilator support ...
Chenliang Zhao, Yongxiang Li, Jinhui Li, Jianrong Xiong   +3 more
wiley   +1 more source

Management of Gaucher Disease Type 1 in a Resource‐Limited Setting: A Pediatric Case Study

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT This case report depicts the management of an 8‐year‐old male with Gaucher Disease Type 1, manifesting as massive splenomegaly, anemia, and skeletal involvement in a resource‐constrained environment. Treated with splenectomy due to the absence of enzyme replacement therapy, it underscores the necessity for enhanced therapeutic access and ...
Bipesh Kumar Shah, Diwakar Koirala, Bivek Mishra, Ramesh Sapkota, Manjil Basnet   +4 more
wiley   +1 more source

РАЦИОНАЛЬНОЕ ЛЕЧЕНИЕ КАШЛЯ НА ЭТАПЕ ПЕРВИЧНОГО МЕДИКО-САНИТАРНОГО ЗВЕНА И В УСЛОВИЯХ СТАЦИОНАРА. ДИСКУССИЯ

Архивъ внутренней медицины, 2013
Archiv vnutrenney meditsiny presents material on rational treatment of cough in modern conditions to physicians and communicating specialists. The article states medical practitioner’s points of view on ambroxol (Ambrobene) and clinical cases where this ...
В. И. Трофимов, Н. А. Былова, И. С. Добротина, Л. Ю. Долинина   +3 more
doaj   +1 more source

Development of directly compressible ambroxol hydrochloride spherical crystals [PDF]

, 2018
One of the longest and most expensive parts of a standard tableting method is granulation. With the application of the direct compression tablet making, granulation can be omitted if the solid compound has proper compressibility and crystallographic ...
Gyulai Orsolya
core  

Rapidly Fatal Multiple Organ Failure of Intravenous Amiodarone: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 10, October 2025.
This graphical abstract illustrates the diagnostic journey of a 75‐year‐old male with severe coughing, breathing difficulties, using the patient's electrocardiogram (ECG) recordings as the pivotal clue for identifying atrial flutter with rapid ventricular response.
BinYu, Hongyan Li, Xiongying Chen
wiley   +1 more source