Results 31 to 40 of about 7,940 (198)

Mitochondrial Function in Enamel Development

Frontiers in Physiology, 2020
Enamel is the most calcified tissue in vertebrates. Enamel formation and mineralization is a two-step process that is mediated by ameloblast cells during their secretory and maturation stages.
Veronica Costiniti, Guilherme H. Bomfim, Yi Li, Erna Mitaishvili, Zhi-wei Ye, Jie Zhang, Danyelle M. Townsend, Marta Giacomello, Marta Giacomello, Rodrigo S. Lacruz   +9 more
doaj   +1 more source

Modeling ameloblast-matrix interactions using 3D cell culture

Frontiers in Physiology, 2022
The distinct morphology adopted by ameloblasts during amelogenesis is highly stage specific and involved intimately with the development of a hierarchical enamel microstructure.
Gayathri Visakan, Rucha Arun Bapat, Jingtan Su, Janet Moradian-Oldak   +3 more
doaj   +1 more source

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig [PDF]

, 2018
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ...
Hedley, J, Murphy, B, Priestnall, S L, Stapleton, N, Wong, H E   +4 more
core   +2 more sources

Towards unraveling the human tooth transcriptome: the dentome. [PDF]

PLoS ONE, 2015
The goal of the study was to characterize the transcriptome profiles of human ameloblasts and odontoblasts, evaluate molecular pathways and advance our knowledge of the human "dentome".
Shijia Hu, Joel Parker, John Timothy Wright   +2 more
doaj   +1 more source

Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ [PDF]

, 2004
Rodents have brownish-yellow incisors whose colour represents their iron content. Iron is deposited into the mature enamel by ameloblasts that outline enamel surface of the teeth.
Ishii Tetsuro, Itoh Ken, Sano Tsuneyoshi, Shibata Yasuaki, Uwayama Junya, Yamaguchi Akira, Yamamoto Masayuki, Yanagawa Toru, Yoshida Hiroshi, 柳川 徹   +9 more
core   +1 more source

Molecular and circadian controls of ameloblasts [PDF]

, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90102/1/j.1600-0722.2011.00918.x ...
Atanasov, Bei, Brown, D’souza, Fincham, Ghoul-Mazgar, Gibson, Hassan, Hu, Hu, Hu, Jernvall, Jin, Kawano, Lezot, Lu, Moffatt, Moffatt, Ohtsuka, Papagerakis, Papagerakis, Papagerakis, Papagerakis, Price, Ribba, Risnes, Simmer, Simmer, Smith, Smith, Uchida, Ukai-Tadenuma, Zheng   +32 more
core   +1 more source

Targeted overexpression of amelotin disrupts the microstructure of dental enamel. [PDF]

PLoS ONE, 2012
We have previously identified amelotin (AMTN) as a novel protein expressed predominantly during the late stages of dental enamel formation, but its role during amelogenesis remains to be determined. In this study we generated transgenic mice that produce
Rodrigo S Lacruz, Yohei Nakayama, James Holcroft, Van Nguyen, Eszter Somogyi-Ganss, Malcolm L Snead, Shane N White, Michael L Paine, Bernhard Ganss   +8 more
doaj   +1 more source

Enamel Defects Associated With Dentin Sialophosphoprotein Mutation in Mice

Frontiers in Physiology, 2021
Dentin sialophosphoprotein (DSPP) is an extracellular matrix protein that is highly expressed in odontoblasts, but only transiently expressed in presecretory ameloblasts during tooth development. We previously generated a knockin mouse model expressing a
Tian Liang, Qian Xu, Hua Zhang, Suzhen Wang, Thomas G. H. Diekwisch, Chunlin Qin, Yongbo Lu   +6 more
doaj   +1 more source

The effect of fluoride on enamel and dentin formation in the uremic rat incisor [PDF]

, 2008
Renal impairment in children is associated with tooth defects that include enamel pitting and hypoplasia. However, the specific effects of uremia on tooth formation are not known.
A Al Nowaiser, AC Karim, Antonius L. J. J. Bronckers, CJ Spak, DM Lyaruu, Donacian M. Lyaruu, E Hossny, Fernando Santos, GP Wysocki, H Husdan, HH Schiffl, IB Salusky, JH Nunn, K Abe, K Nasstrom, M Torra, MB Leonard, MJ Koch, O Fejerskov, P Farge, Pamela DenBesten, PK Denbesten, PN Scutellari, Robert Mathias, RS Mathias, RS Mathias, T Murayama, VS Lucas, W Beertsen   +28 more
core   +1 more source

Sodium-Calcium Exchangers in Rat Ameloblasts

Journal of Pharmacological Sciences, 2010
Although the central role of ameloblasts in synthesis and resorption of enamel matrix proteins during amelogenesis is well documented, the Ca2+-transport/extrusion mechanism remains to be fully elucidated. To clarify Ca2+-transport in rat ameloblasts, we
Reijiro Okumura, Yoshiyuki Shibukawa, Takashi Muramatsu, Sadamitsu Hashimoto, Kan-Ichi Nakagawa, Masakazu Tazaki, Masaki Shimono   +6 more
doaj   +1 more source