Results 61 to 70 of about 3,471 (217)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

α-Glucosidase and 15-Lipoxygenase Inhibitory Activities of Phytochemicals from

Natural Product Communications, 2015
A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone.
Nurul Iman Aminudin, Farediah Ahmad, Muhammad Taher, Razauden Mohamed Zulkifli   +3 more
doaj   +1 more source

Deep Eutectic Solvents Extraction and Optimization of Amentoflavone from Selaginella moellendorffii

Shipin gongye ke-ji, 2022
To extract the amentoflavone (AME) from Selaginella moellendorffii with deep eutectic solvent technology, three kinds of deep eutectic solvents were prepared by one-step method, and the best deep eutectic solvent for extracting AME of Selaginella ...
Chao LIU, Weiwei LI, Jie LEI, Gang LI, Demin LU, Dajun XU, Xiaona SHENG, Mingjiang WU, Gang WANG   +8 more
doaj   +1 more source

Phytochemistry of the genus Selaginella (Selaginellaceae). [PDF]

, 2014
The Selaginellaceae family includes the single genus Selaginella, which is found worldwide and comprises approximately 700 to 750 species. A number of species have been traditionally used for medicinal purposes in the whole world, and the phytochemistry ...
ALMEIDA, J. R. G. da S., BARBOSA FILHO, J. M., MACEDO, L. A. R. de O., OLIVEIRA, V. R. de, SIQUEIRA FILHO, J. A. de, SÁ, P. G. S. de   +5 more
core  

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, Volume 40, Issue 5, Page 2380-2396, May 2026.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

Antidiabetic Activity and Potential Mechanism of Amentoflavone in Diabetic Mice

Molecules, 2019
Aim: To investigate the anti-diabetic activity of amentoflavone (AME) in diabetic mice, and to explore the potential mechanisms. Methods: Diabetic mice induced by high fat diet and streptozotocin were administered with amentoflavone for 8 weeks. Biochemical indexes were tested to evaluate its anti-diabetic effect.
Chengfu Su, Chuanbin Yang, Man Gong, Yingying Ke, Peipei Yuan, Xiaolan Wang, Min Li, Xiaoke Zheng, Weisheng Feng   +8 more
openaire   +3 more sources

Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1 [PDF]

, 2016
Camptothecin (CPT), a topoisomerase I (TOP1) inhibitor, exhibits anti-tumor activity against a wide range of tumors. Redundancy of TOP1-mediated repair mechanisms is a major challenge facing the efficiency of TOP1-targetting therapies. This study aims to
El-Khamisy, S.F., El-Shafie, L., Elsayed, W., Farag, M.A., Hassan, M.K.   +4 more
core   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, Volume 13, Issue 21, 13 April 2026.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Antibacterial Effect of Amentoflavone and Its Synergistic Effect with Antibiotics

Journal of Microbiology and Biotechnology, 2013
Selaginella tamariscina is a traditional herb used in medicine. Phytochemical amentoflavone, a biflavonoid class of flavonoids, was isolated from the plant of Selaginella tamariscina. In this study, the antibacterial effects and combination effects of amentoflavone and conventional antibiotics such as ampicillin, cefotaxime, and chloramphenicol were ...
Ji Hong, Hwang, Hyemin, Choi, Eun-Rhan, Woo, Dong Gun, Lee   +3 more
openaire   +2 more sources

Amentoflavone-Enriched Selaginella rossii Warb. Suppresses Body Weight and Hyperglycemia by Inhibiting Intestinal Lipid Absorption in Mice Fed a High-Fat Diet

Life, 2022
Many Selaginellaceae species are used as traditional medicines in Asia. This study is the first to investigate the anti-obesity and anti-diabetic effects of Selaginella rossii (SR) in high-fat diet (HFD)–fed C57BL/6J mice.
Hwa Lee, Seona Cho, Soo-Yong Kim, Jeongha Ju, Sang Woo Lee, Sangho Choi, Hulin Li, Renzhe Piao, Ho-Yong Park, Tae-Sook Jeong   +9 more
doaj   +1 more source