Results 11 to 20 of about 750,316 (378)

An amide cyclophane [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2014
The title compound, 8,18-dithia-2,6-diaza-13(1,4)-piperidina-1(1,2),4(1,3),7(1,2)-tribenzenaoctadecaphane-10,15-diyne-3,6-dione, C32H30N4O2S2, is composed of a relatively planar bis(2-mercaptophenyl)isophthalamide unit linked to a bridging 1,4-di(but-2-yn-1-yl)piperazine unit, forming a macrocycle.
Vijayan Viswanathan   +3 more
openaire   +3 more sources

Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity

open access: yesJournal of Medicinal Chemistry, 2021
Criteria for predicting the druglike properties of “beyond Rule of 5” Proteolysis Targeting Chimeras (PROTAC) degraders are underdeveloped. PROTAC components are often combined via amide couplings due to their reliability.
Victoria G Klein   +4 more
semanticscholar   +1 more source

Synthesis and Estimation of the Insecticide and Antibacterial Activities for Some New Amide Derivatives

open access: yesIndonesian Journal of Chemistry, 2023
In this work, new compounds of amide derivatives (C1-C3) were synthesized through the conversion reaction of p-chloroaniline to diazonium salt (B1), which reacts with aniline to form a new azo-compound (B3).
Zinah Hussein Ali   +4 more
doaj   +1 more source

Synthesis and RP-TLC lipophilicity evaluation of a novel fluocinolon acetonide soft drug derivative [PDF]

open access: yesKragujevac Journal of Science, 2016
Cortienic acid was obtained by periodic acid oxidation of fluocinolone acetonide, whereas corresponding amide was synthesized from the cortienic acid and ethyl ester of b-alanine by dicyclohexylcarbodiimide - hydroxybenzotriazole coupling procedure ...
Dobričić Vladimir   +2 more
doaj   +1 more source

Synthesis of Functionalized N-(4-Bromophenyl)furan-2-carboxamides via Suzuki-Miyaura Cross-Coupling: Anti-Bacterial Activities against Clinically Isolated Drug Resistant A. baumannii, K. pneumoniae, E. cloacae and MRSA and Its Validation via a Computational Approach

open access: yesPharmaceuticals, 2022
N-(4-bromophenyl)furan-2-carboxamide (3) was synthesized by the reaction furan-2-carbonyl chloride (1) and 4-bromoaniline (2) in the presence of Et3N in excellent yields of 94%.
Ayesha Siddiqa   +9 more
doaj   +1 more source

Sum frequency generation spectroscopy of the attachment disc of a spider [PDF]

open access: yes, 2021
The pyriform silk of the attachment disc of a spider was studied using infrared-visible vibrational sum frequency generation (SFG) spectroscopy. The spider can attach dragline and radial lines to many kinds of substrates in nature (concrete, alloy, metal,
Hien, Khuat Thi Thu   +5 more
core   +2 more sources

Interface chemistry of an amide electrolyte for highly reversible lithium metal batteries

open access: yesNature Communications, 2020
Metallic lithium is a promising anode to increase the energy density of rechargeable lithium batteries. Despite extensive efforts, detrimental reactivity of lithium metal with electrolytes and uncontrolled dendrite growth remain challenging ...
Qidi Wang   +11 more
semanticscholar   +1 more source

Progress in C-C and C-Heteroatom Bonds Construction Using Alcohols as Acyl Precursors

open access: yesMolecules, 2022
Acyl moiety is a common structural unit in organic molecules, thus acylation methods have been widely explored to construct various functional compounds.
Feng Zhao   +4 more
doaj   +1 more source

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis. [PDF]

open access: yes, 2016
A long-standing challenge in synthetic chemistry is the development of the transamidation reaction. This process, which involves the conversion of one amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors. Although some
Anthony, Sarah M   +4 more
core   +2 more sources

Nickel-catalyzed transamidation of aliphatic amide derivatives. [PDF]

open access: yes, 2017
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained ...
Baker, Emma L   +2 more
core   +1 more source

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