Amide-Amide and Amide-Water Hydrogen Bonds: Implications for Protein Folding and Stability [PDF]
Journal of the American Chemical Society, 1994 Amide-amide hydrogen bonds have been implicated in directing protein folding and enhancing protein stability. Inversion transfer (13)C NMR spectroscopy and IR spectroscopy were used to compare the ability of various amide solvents and of water to alter the rate of the cis-trans isomerization of the prolyl peptide bond of Ac-Gly-[β,δ-(13)C]Pro-OMe and ...
Ronald T. Raines, Eric S. Eberhardt
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Amide nitrogen pyramidalization changes lactam amide spinning [PDF]
Nature Communications, 2019 AbstractAlthough cis-trans lactam amide rotation is fundamentally important, it has been little studied, except for a report on peptide-based lactams. Here, we find a consistent relationship between the lactam amide cis/trans ratios and the rotation rates between the trans and cis lactam amides upon the lactam chain length of the stapling side-chain of
Yuko Otani +8 more
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Metabolism of amino acid amides in Pseudomonas putida ATCC 12633 [PDF]
, 1993 The metabolism of the natural amino acid L-valine, the unnatural amino acids D-valine, and D-, L-phenylglycine (D-, L-PG), and the unnatural amino acid amides D-, L-phenylglycine amide (D, L-PG-NH2) and L-valine amide (L-Val-NH2) was studied in ...
Croes, L.M., +4 more
core +1 more source
Raman spectra of crystalline secondary amides [PDF]
, 2017 The study of single-crystal Raman spectra of a series of crystalline secondary amides (acetanilide, methacetin, phenacetine, orthorhombic and monoclinic polymorphs of paracetamol) as well as simple amides formanilide and benzanilide in the temperature range 5-300 K was carried out.
arxiv +1 more source
Cyclic Peptoid-Peptide Hybrids as Versatile Molecular Transporters
Frontiers in Chemistry, 2021 Addressing intracellular targets is a challenging task that requires potent molecular transporters capable to deliver various cargos. Herein, we report the synthesis of hydrophobic macrocycles composed of both amino acids and peptoid monomers. The cyclic
Claudine Nicole Herlan +6 more
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Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]
, 2019 Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde +5 more
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Measurement-induced disturbances and nonclassical correlations of Gaussian states [PDF]
Phys. Rev. A 83, 042325 (2011), 2010 We study quantum correlations beyond entanglement in two-mode Gaussian states of continuous variable systems, by means of the measurement-induced disturbance (MID) and its ameliorated version (AMID). In analogy with the recent studies of the Gaussian quantum discord, we define a Gaussian AMID by constraining the optimization to all bi-local Gaussian ...
arxiv +1 more source
Biologically Active Compounds. II. The Synthesis of β-CarboxY-γ-butyrolactone Derivatives [PDF]
, 1968 Amide derivatives of γ-substituted paraconic and aconic acids have been synthesized. Ultraviolet spectra of the aconic acid derivatives showed characteristic fine structure in the region of 245 to 280 ...
Isikawa, Tatsuo +2 more
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Synthesis and Antifungal Activity of Pyrimidine Derivatives Containing an Amide Moiety
Frontiers in Chemistry, 2021 In this study, 17 novel pyrimidine derivatives containing an amide moiety were synthesized. Then their in vitro antifungal activities against Botryosphaeria dothidea (B. dothidea), Phomopsis sp., and Botrytis cinereal (B. cinereal) were determined.
Wenneng Wu +3 more
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Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics [PDF]
, 2013 We present the ProCS method for the rapid and accurate prediction of protein backbone amide proton chemical shifts - sensitive probes of the geometry of key hydrogen bonds that determine protein structure.
Boomsma, Wouter +6 more
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