A Self-Immolative Linker for the pH-Responsive Release of Amides
Molecules, 2023 The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking the
Agnese Petrini +4 more
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One-Pot Synthesis of Single-Source Precursors for Nanocrystalline LED Phosphors M2Si5N8:Eu2+ (M = Sr, Ba) [PDF]
, 2009 Highly efficient red-emitting nitridosilicate phosphors Sr2Si5N8:Eu2+ and Ba1.5Sr0.5Si5N8:Eu2+ (doping level 1%) applicable to phosphor converted pc-LEDs were synthesized in nanocrystalline form at low temperatures employing a novel single-source ...
Schmidt, Peter J. +2 more
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Molecules, 2023 Pseudomonas aeruginosa is an opportunistic pathogen responsible for many nosocomial infections. This bacterium uses Quorum Sensing (QS) to generate antimicrobial resistance (AMR) so its disruption is considered a novel approach.
Lida V. Hernández-Moreno +3 more
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Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines [PDF]
, 2012 The asymmetric synthesis of new chiral gamma-chloro-alpha,beta-diaminocarboxylamide derivatives by highly diastereoselective Mannich-type reactions of N-(diphenylmethylene) glycinamides across chiral alpha-chloro-N-p-toluenesulfinylaldimines was ...
Augustyns, Koen +5 more
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AMIDES ISOLATED FROM THE LEAVES OF Piper tuberculatum Jacq. (Piperaceae) WITH ACETYLCHOLINESTERASE INHIBITION AND LARVICIDAL ACTIVITY AGAINST Aedes aegypti [PDF]
Química NovaPiper tuberculatum Jacq. is known to be a promising source of amides, which have shown remarkable biological activities. In this study, a phytochemical investigation of the leaves of P.
Brenda R. C. Leocadio +10 more
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Fully Chlorinated N-Silyl Amides of Titanium and Tungsten [PDF]
, 1997 The reaction of hexachlorodisilazanyllithium (Cl3Si)2NLi (1), with TiCl4 leads selectively to the novel fully chlorinated amides (Cl3Si)2NTiCl3 (2) or [(Cl3Si)2N]2 TiCl2 (3), respectively, depending on the molar ratio of the starting materials.
Milius, Wolfgang +2 more
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Beilstein Journal of Organic Chemistry, 2013 A self-condensation cyclization reaction mediated by phosphorus pentoxide (P2O5) and catalyzed by zinc bromide (ZnBr2) is presented for the synthesis of polysubstituted 4-pyridones and 2-pyridones from β-keto amides.
Liquan Tan +3 more
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Metabolism of amino acid amides in Pseudomonas putida ATCC 12633 [PDF]
, 1993 The metabolism of the natural amino acid L-valine, the unnatural amino acids D-valine, and D-, L-phenylglycine (D-, L-PG), and the unnatural amino acid amides D-, L-phenylglycine amide (D, L-PG-NH2) and L-valine amide (L-Val-NH2) was studied in ...
Croes, L.M., +4 more
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Tandem aza-Claisen rearrangement and ring closing metathesis reactions: the stereoselective synthesis of functionalised carbocyclic amides [PDF]
, 2009 A one-pot, tandem process has been developed for the efficient synthesis of functionalised carbocyclic amides. A substituted cyclopentenyl trichloroacetamide was synthesised using a tandem thermal aza-Claisen rearrangement and RCM process, while an ...
Donaldson, A. +2 more
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KNH2 - KH: a metal amide - hydride solid solution [PDF]
, 2016 We report for the first time the formation of a metal amide-hydride solid solution. The dissolution of KH into KNH2 leads to an anionic substitution, which decreases the interaction among NH2 - ions.
Baricco, Marcello +15 more
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