Results 11 to 20 of about 128 (98)

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

Beilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin, Vera Berseneva, Tetyana Beryozkina, Tatiana Glukhareva, Lidia Dianova, Wim Dehaen, Eugenia Seliverstova, Vasiliy Bakulev   +7 more
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Modern chemical disinfectants and antiseptics. Part I

Журнал органічної та фармацевтичної хімії, 2021
Aim. To generalize and systematize information on the properties of modern chemical disinfectants and antiseptic agents (DA and AA). Results and discussion.
Vasyl M. Britsun, Nataliya V. Simurova, Inna V. Popova, Oleksii V. Simurov   +3 more
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Principais métodos de síntese de amidinas

Química Nova, 2006
The amidine functional group is found in a wide range of natural products and is biologically active against several pathogens. In addition, amidines have long been regarded as useful intermediates in the synthesis of heterocyclic compounds. Consequently,
Maurício Silva dos Santos, Alice Maria Rolim Bernardino, Marcos Costa de Souza   +2 more
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Biological Activity of Newly Synthesized Benzimidazole and Benzothizole 2,5-Disubstituted Furane Derivatives

Molecules, 2021
Newly designed and synthesized cyano, amidino and acrylonitrile 2,5-disubstituted furane derivatives with either benzimidazole/benzothiazole nuclei have been evaluated for antitumor and antimicrobial activity.
Livio Racané, Ivo Zlatar, Nataša Perin, Maja Cindrić, Vedrana Radovanović, Mihailo Banjanac, Suresh Shanmugam, Marijana Radić Stojković, Karmen Brajša, Marijana Hranjec   +9 more
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Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses

Molecules, 2021
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent and drug-resistant HSV infections.
Anita Toscani, Rossana Denaro, Sergio Fernando Castillo Pacheco, Matteo Biolatti, Silvia Anselmi, Valentina Dell’Oste, Daniele Castagnolo   +6 more
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Hypotheses for synthesis of novel chiral beta-amino-beta-lactams through amidines

Results in Chemistry, 2021
Synthesis of new beta-lactams is an attractive field because some of these types of molecules are biologically active. The design and preparation of C4-nitrogen-substituted beta-lactams are not known.
Bimal Krishna Banik, Alberto Boretti
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Copper-Catalyzed One-Pot Synthesis of N-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides

Molecules, 2021
N-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature.
Yu Zhao, Zitong Zhou, Man Chen, Weiguang Yang   +3 more
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Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Newly synthesised benzimidazole/benzotiazole derivatives bearing amidino, namely 3,4,5,6-tetrahydropyrimidin-1-ium chloride, substituents have been evaluated for their potential antitumor activity in vitro.
Livio Racané, Maja Cindrić, Ivo Zlatar, Tatjana Kezele, Astrid Milić, Karmen Brajša, Marijana Hranjec   +6 more
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Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides

Pathogens, 2023
Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of two A.
Ennya Rafaella Neves Cardoso, Stephani Félix Carvalho, Sarah Alves Dias, Rayane Almeida Santos, Mariana Avelar Tavares, Lucianne Cardoso Neves, Warley Vieira de Freitas Paula, Gracielle Teles Pádua, Nicolas Jalowitzki de Lima, Raquel Loren dos Reis Paludo, Isabela Santos Silva, Raphaela Bueno Mendes Bittencourt, Gabriel Cândido dos Santos, Flavia Giovana de Jesus Nascimento, Luiza Gabriella Ferreira de Paula, Filipe Dantas-Torres, Caio Marcio De Oliveira Monteiro, Felipe da Silva Krawczak   +17 more
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Iron-catalyzed [4 + 2] annulation of amidines with α,β-unsaturated ketoxime acetates toward 2,4,6-trisubstituted pyrimidines

Green Synthesis and Catalysis, 2023
An iron-catalyzed [4 ​+ ​2] annulation of amidines with α,β-unsaturated ketoxime acetates is described. This strategy employs amidines as CN units and provides a new protocol for the construction of 2,4,6-trisubstituted pyrimidines under batch and ...
Qinghuan Wu, Luchao Li, Binyan Xu, Jie Sun, Dong Ji, Yuguang Li, Lei Shen, Zheng Fang, Jindian Duan, Beining Chen, Kai Guo   +10 more
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