Results 11 to 20 of about 7,050 (214)

A General Group Testing Strategy for Discovering Chemical Cooperativity. [PDF]

Angew Chem Int Ed Engl
A combinatorial design theory‐based group testing strategy coupled with luminescence screening to uncover cooperative interactions in a large combinatorial space. Iterative deconvolution identifies reactive molecular pairs and enables the discovery of trifluoromethylthiolation (SCF3) reagents.
Pflüger PM, Katzenburg F, Sandfort F, Teders M, Gómez-Suárez A, Standley EA, Hopkinson MN, Daniliuc CG, Heuer A, Glorius F.   +9 more
europepmc   +3 more sources

Triflamidation of Allyl-Containing Substances:Unusual Dehydrobromination vs. Intramolecular Heterocyclization

Molecules, 2022
Allyl halides with triflamide under oxidative conditions form halogen-substituted amidines. Allyl cyanide reacts with triflamide in acetonitrile or THF solutions in the presence of NBS to give the products of bromotriflamidation with a solvent ...
Anton S. Ganin, Mikhail Yu. Moskalik, Ivan A. Garagan, Vera V. Astakhova, Bagrat A. Shainyan   +4 more
doaj   +1 more source

Modern chemical disinfectants and antiseptics. Part I

Журнал органічної та фармацевтичної хімії, 2021
Aim. To generalize and systematize information on the properties of modern chemical disinfectants and antiseptic agents (DA and AA). Results and discussion.
Vasyl M. Britsun, Nataliya V. Simurova, Inna V. Popova, Oleksii V. Simurov   +3 more
doaj   +1 more source

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

Beilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin, Vera Berseneva, Tetyana Beryozkina, Tatiana Glukhareva, Lidia Dianova, Wim Dehaen, Eugenia Seliverstova, Vasiliy Bakulev   +7 more
doaj   +1 more source

Acaricide resistance of Rhipicephalus decoloratus ticks collected from communal grazing cattle in South Africa

Journal of Advanced Veterinary and Animal Research, 2022
Objective: This study aimed to determine acaricide resistance in Rhipicephalus decoloratus ticks collected from grazing cattle between November 2018 and May 2019 in Elundini, Senqu, and Walter Sisulu Local Municipalities in the northeastern region of the
Mandla Yawa, Nkululeko Nyangiwe, Ishmael Festus Jaja, Munyaradzi Christopher Marufu, Charles T. Kadzere   +4 more
doaj   +1 more source

Principais métodos de síntese de amidinas

Química Nova, 2006
The amidine functional group is found in a wide range of natural products and is biologically active against several pathogens. In addition, amidines have long been regarded as useful intermediates in the synthesis of heterocyclic compounds. Consequently,
Maurício Silva dos Santos, Alice Maria Rolim Bernardino, Marcos Costa de Souza   +2 more
doaj   +1 more source

Green fluorescent diamidines as diagnostic probes for trypanosomes [PDF]

, 2014
LED fluorescence microscopy offers potential benefits to the diagnosis of human African trypanosomiasis, as well as to other aspects of diseases management, such as detection of drug resistant strains.
Arvind Kumar, Bailey, Baker, Barrett, Bieler, Bridges, Carter, Chappuis, David W. Boykin, de Koning, Federica Giordani, Hanscheid, Jones, Keiser, Lanteri, Manoj Munde, Mathis, Mathis, Matovu, Michael P. Barrett, Minion, Mohamed A. Ismail, Paine, Steingart, Stewart, Vincent, W. David Wilson, Wilson   +27 more
core   +1 more source

Copper-Catalyzed One-Pot Synthesis of N-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides

Molecules, 2021
N-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature.
Yu Zhao, Zitong Zhou, Man Chen, Weiguang Yang   +3 more
doaj   +1 more source

Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses

Molecules, 2021
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent and drug-resistant HSV infections.
Anita Toscani, Rossana Denaro, Sergio Fernando Castillo Pacheco, Matteo Biolatti, Silvia Anselmi, Valentina Dell’Oste, Daniele Castagnolo   +6 more
doaj   +1 more source

Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides

Pathogens, 2023
Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of two A.
Ennya Rafaella Neves Cardoso, Stephani Félix Carvalho, Sarah Alves Dias, Rayane Almeida Santos, Mariana Avelar Tavares, Lucianne Cardoso Neves, Warley Vieira de Freitas Paula, Gracielle Teles Pádua, Nicolas Jalowitzki de Lima, Raquel Loren dos Reis Paludo, Isabela Santos Silva, Raphaela Bueno Mendes Bittencourt, Gabriel Cândido dos Santos, Flavia Giovana de Jesus Nascimento, Luiza Gabriella Ferreira de Paula, Filipe Dantas-Torres, Caio Marcio De Oliveira Monteiro, Felipe da Silva Krawczak   +17 more
doaj   +1 more source