Results 21 to 30 of about 7,050 (214)

Biological Activity of Newly Synthesized Benzimidazole and Benzothizole 2,5-Disubstituted Furane Derivatives

open access: yesMolecules, 2021
Newly designed and synthesized cyano, amidino and acrylonitrile 2,5-disubstituted furane derivatives with either benzimidazole/benzothiazole nuclei have been evaluated for antitumor and antimicrobial activity.
Livio Racané   +9 more
doaj   +1 more source

Biological Activity of Amidino-Substituted Imidazo [4,5-b]pyridines

open access: yesMolecules, 2022
A series of cyano- and amidino-substituted imidazo[4,5-b]pyridines were synthesized using standard methods of organic synthesis, and their biological activity was evaluated.
Ida Boček Pavlinac   +8 more
doaj   +1 more source

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]

open access: yes, 2017
Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
core   +1 more source

Three-Component Reaction of Tautomeric Amidines with 3-Ferrocenylmethylidene-2,4-pentanedione. Formation of Polymeric Coordination Complexes of Potassium Ferrocenyl-(hexahydro)pyrimidoxides

open access: yesMolecules, 2013
Acetamidine hydrochloride and p-aminobenzamidine dihydrochloride interact with 3-ferrocenylmethylidene-2,4-pentanedione at 80–82 °C in the presence of K2CO3 in the water–alcohol medium in two tautomeric forms (the amidoimine and enediamine ones) with ...
Elena I. Klimova   +4 more
doaj   +1 more source

Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Newly synthesised benzimidazole/benzotiazole derivatives bearing amidino, namely 3,4,5,6-tetrahydropyrimidin-1-ium chloride, substituents have been evaluated for their potential antitumor activity in vitro.
Livio Racané   +6 more
doaj   +1 more source

Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles

open access: yesMolecules, 2022
A pseudo-three-component synthesis of N-aroylmethylimidazoles 3 with three new C–N bonds formed regioselectively under microwave conditions was developed.
Nerith Rocio Elejalde-Cadena   +5 more
doaj   +1 more source

Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]

open access: yes, 2006
Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille   +3 more
core   +4 more sources

Synthesis of Fully Substituted Pyrimidines [PDF]

open access: yes, 2016
A novel approach to the synthesis of fully substituted pyrimidine derivatives armed with an oxy-functionalized acetate chain at the ring is described. The manifold uses amidines as the nitrogen source and activated skipped diynes as the electrophilic
García-Tellado, Fernando   +2 more
core   +2 more sources

Synthetic studies towards bottromycin

open access: yesBeilstein Journal of Organic Chemistry, 2012
Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion.
Stefanie Ackermann   +4 more
doaj   +1 more source

Quantitative determination of 0.05 % chlorhexidine solution by capillary electrophoresis

open access: yesZaporožskij Medicinskij Žurnal, 2019
The aim of the work was to estimate the quantitative content of 0.05 % chlorhexidine solution by capillary electrophoresis. Materials and methods.
A. M. Sampiiev   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy