Results 91 to 100 of about 12,409 (229)

Folate Interaction With Genetic Risk for Neural Tube Defects Among Infants in Bangladesh

Birth Defects Research, Volume 117, Issue 12, December 2025.
ABSTRACT Background Neural tube defects such as spina bifida (SB) are congenital anomalies associated with significant morbidity and mortality worldwide. Environmental factors, particularly folate, modify SB risk. Based on recurrence rates of SB within families, genetic risk also contributes to SB development.
Enrique Mondragon‐Estrada, Xingyan Wang, Michael D. Uhler, Afifah Farooque, Kelly Liu, Sudipta Kumer Mukherjee, Sheikh Muhammad Ekramullah, D. M. Arman, Joynul Islam, Hafiza Sultana Suchanda, David C. Christiani, Benjamin C. Warf, Maitreyi Mazumdar, Sarah U. Morton   +13 more
wiley   +1 more source

A Mouse Amidase Specific for N-terminal Asparagine: the gene, the enzyme, and their function in the N-end rule pathway [PDF]

, 1996
The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. In both fungi and mammals, the tertiary destabilizing N-terminal residues asparagine and glutamine function through their conversion, by enzymatic ...
Arfin, Stuart M., Bradshaw, Ralph A., Copeland, Neal G., Grigoryev, Sergei, Jenkins, Nancy A., Kwon, Yong Tae, Stewart, Albert E., Varshavsky, Alexander   +7 more
core  

Creatinine biosensors: principles and designs [PDF]

, 2000
Creatinine biosensors, based on both potentiometric and amperometric devices, have been created. However, there are significant problems still to be addressed, including the balance between sensitivity and selectivity, interference rejection and sensor
Killard, Anthony J., Smyth, Malcolm R.
core   +1 more source

Structural Investigations of N-carbamoylputrescine Amidohydrolase from Medicago truncatula: Insights into the Ultimate Step of Putrescine Biosynthesis in Plants

Frontiers in Plant Science, 2016
Putrescine, 1,4-diaminobutane, is an intermediate in the biosynthesis of more complexed polyamines, spermidine and spermine. Unlike other eukaryotes, plants have evolved a multistep pathway for putrescine biosynthesis that utilizes arginine. In the final
B. Sekuła, M. Ruszkowski, M. Malińska, Z. Dauter   +3 more
semanticscholar   +1 more source

Exploration of Human Skin Phageome to Reveal Endolysins and Novel Antimicrobial Peptides for Therapeutic Applications

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study uncovers diverse endolysins and novel antimicrobial peptides from the human skin phageome, highlighting their potential to target antibiotic‐resistant pathogens and disrupt virulence mechanisms, paving the way for next‐generation skin therapeutics.
Jibon Kumar Paul, Arzuba Akter, Nurnabi Azad Jewel, Mohimenul Haque Rolin, Daniyal Karim, Raphael Kabir Niloy, Shakhinur Islam Mondal   +6 more
wiley   +1 more source

Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana [PDF]

, 2006
Amidase 1 (AMI1) from Arabidopsis thaliana converts indole-3-acetamide (IAM), into indole-3-acetic acid (IAA). AMI1 is part of a small isogene family comprising seven members in A.
A Müller, A Müller, A Vojta, A Wachter, AM Metz, AW Woodward, BA Stelmach, BF Cravatt, Daniel Neu, DE Saslowsky, DK Giang, E Kemper, Elmar W. Weiler, EW Weiler, FA Ausubel, H Towbin, J Haseloff, J Sambrook, J-F Mayaux, JJ Finer, K Sohrt, KD Scharf, M Kawaguchi, M Kawaguchi, M Kobayashi, M Madera, M Saotome, MH Bracey, MM Bradford, MP Patricelli, NM Upadhyaya, NR Hofmann, O Chew, O Kleiner, Oliver Berkowitz, R Shrestha, R Shrestha, S Brenner, S Pollmann, S Pollmann, S Shin, S Shin, S Vorwerk, SR Cutler, Stephan Pollmann, T Murashige, Thomas Lehmann, Tina Schäfer, VS Reddy, WB Bruce, Y Arai, YJ Lee, YQ An, YS Kim   +53 more
core   +2 more sources

Activation of the Dimer of 3, 4‐dimethylphenol Production From Marine Streptomyces sp. FJNU027 Under Oligotrophic Condition

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study assessed the potential for secondary metabolites production of marine Streptomyces sp. FJNU027 under various media. It was found the FJNU027 strain produced a differential compound in oligotrophic medium. The pure compound was obtained through mass fermentation, extraction and isolation, and identified as the dimer of 3, 4‐dimethylphenol ...
Feifei Wang, Huimin Yuan, Cuie Bai, Haiyan Li, Li Xu, Lingjun Yu, Lianzhong Luo, Yongbiao Zheng   +7 more
wiley   +1 more source

Bacterio-plankton transformation of diazepam and 2-amino-5-chlorobenzophenone in river waters. [PDF]

, 2014
Benzodiazepines are a large class of commonly-prescribed drugs used to treat a variety of clinical disorders. They have been shown to produce ecological effects at environmental concentrations, making understanding their fate in aquatic environments very
Ainsworth, Bianchi, Boxall, Brodin, Brooks, Calisto, Calisto, Cole, Crump, Diaz-Cruz, Gardolinski, Griffiths, Guenet, Halling-Sørensen, Helbling, Holmes, Ibekwe, Kan, Kosjek, Kümmerer, Lane, Liu, Loffler, Muyzer, Muyzer, Nercessian, Onesios-Barry, Porter, Shimp, Straub, Stuer-Lauridsen, Suzuki, Tappin, Tappin, Ternes, Verlicchi, West, WHO, Yoon, Zuccato   +39 more
core   +3 more sources

The role of conserved Cys residues in Brassica rapa auxin amidohydrolase: Cys139 is crucial for the enzyme activity and Cys320 regulates enzyme stability.

Physical Chemistry, Chemical Physics - PCCP, 2016
Brassica rapa auxin amidohydrolase (BrILL2) participates in the homeostasis of the plant hormones auxins by hydrolyzing the amino acid conjugates of auxins, thereby releasing the free active form of hormones.
Ana Smolko, Filip Šupljika, J. Martinčić, N. Jajčanin-Jozić, Marina Grabar-Branilović, S. Tomić, J. Ludwig-Müller, I. Piantanida, B. Salopek-Sondi   +8 more
semanticscholar   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source