Results 111 to 120 of about 10,587 (231)

The role of two families of bacterial enzymes in putrescine synthesis from agmatine via agmatine deiminase [PDF]

open access: yes, 2011
Putrescine, one of the main biogenic amines associated to microbial food spoilage, can be formed by bacteriafrom arginine via ornithine decarboxylase (ODC), or from agmatine via agmatine deiminase (AgDI).
Isabel Pardo   +4 more
core  

Overexpression and knockdown of cotton GhdadD gene reveals its drought and salt stress tolerance role

open access: yesiScience
Summary: The 5′-deoxyadenosine deaminase (DADD), a member of the amidohydrolase family regulates biological purine metabolism. In this study, bioinformatic analysis, overexpression and knockdown of GhdadD gene were detected to identify its potential role
Yuanyuan Zhang   +11 more
doaj   +1 more source

Genetic diversity of Leptospira in northwestern Colombia: first report of Leptospira santarosai as a recognised leptospirosis agent

open access: yesMemorias do Instituto Oswaldo Cruz
The region of Antioquia in northeastern Colombia has the highest number of reported leptospirosis cases in the country. It also shows high seroprevalence indexes in the general population and socio-environmental conditions favourable for the transmission
Ronald Guillermo Peláez Sanchez   +4 more
doaj   +1 more source

Overexpression of acid ceramidase (ASAH1) protects retinal cells (ARPE19) from oxidative stress[S]

open access: yesJournal of Lipid Research, 2019
Over 11 million people in the United States alone have some form of age-related macular degeneration (AMD). Oxidative stress, cell death, and the degeneration of retinal pigment epithelial (RPE) cells contribute to AMD pathology. Recent evidence suggests
Eriko Sugano   +9 more
doaj   +1 more source

A New Strategy to Inhibit Scar Formation by Accelerating Normal Healing Using Silicate Bioactive Materials

open access: yesAdvanced Science
Inspired by the scar‐free wound healing in infants, an anti‐scar strategy is proposed by accelerating wound healing using silicate bioactive materials.
Zhaowenbin Zhang   +10 more
doaj   +1 more source

Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase from Pseudomonas aeruginosa PAO1

open access: yesBioinorganic Chemistry and Applications, 2018
Dihydropyrimidinase, a dimetalloenzyme containing a carboxylated lysine within the active site, is a member of the cyclic amidohydrolase family, which also includes allantoinase, dihydroorotase, hydantoinase, and imidase.
Jen-Hao Cheng   +3 more
doaj   +1 more source

Studies on the Zn2+/Co2+ Exchange with Acylamino Acid Amidohydrolase from Pig Kidney [PDF]

open access: hybrid, 1981
Eckhard Kumpe   +2 more
openalex   +1 more source

ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability

open access: yesCell Death and Disease
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to metastasis and therapy resistance. Owing to its aggressive nature and limited availability of targeted therapies, TNBC is associated with higher mortality as compared to ...
Kiran Kumar Reddi   +5 more
doaj   +1 more source

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