Results 51 to 60 of about 12,409 (229)

Local inhibition of nitrogen fixation and nodule metabolism in drought-stressed soybean [PDF]

, 2013
Drought stress is a major factor limiting symbiotic nitrogen fixation (NF) in soybean crop production. However, the regulatory mechanisms involved in this inhibition are still controversial.
Arrese-Igor, César, Díaz Leal, Juan Luis, Gil-Quintana, Erena, González, Esther M., Larrainzar, Estíbaliz, Muñoz Alamillo, Josefa, Pineda Priego, Manuel, Seminario, Amaia, Wienkoop, Stefanie   +8 more
core   +1 more source

Probing the Active Site of Class 3 L-Asparaginase by Mutagenesis: Mutations of the Ser-Lys Tandems of ReAV

Biomolecules
The ReAV enzyme from Rhizobium etli, a representative of Class 3 L-asparaginases, is sequentially and structurally different from other known L-asparaginases. This distinctiveness makes ReAV a candidate for novel antileukemic therapies.
Kinga Pokrywka, Marta Grzechowiak, Joanna Sliwiak, Paulina Worsztynowicz, Joanna I. Loch, Milosz Ruszkowski, Miroslaw Gilski, Mariusz Jaskolski   +7 more
doaj   +1 more source

SKN-1 regulates stress resistance downstream of amino catabolism pathways

iScience, 2022
Summary: The deleterious potential to generate oxidative stress is a fundamental challenge to metabolism. The oxidative stress response transcription factor, SKN-1/NRF2, can sense and respond to changes in metabolic state, although the mechanism and ...
Phillip A. Frankino, Talha F. Siddiqi, Theodore Bolas, Raz Bar-Ziv, Holly K. Gildea, Hanlin Zhang, Ryo Higuchi-Sanabria, Andrew Dillin   +7 more
doaj   +1 more source

How innate immunity proteins kill bacteria and why they are not prone to resistance [PDF]

, 2017
Recent advances on antibacterial activity of peptidoglycan recognition proteins (PGRPs) offer some insight into how innate immunity has retained its antimicrobial effectiveness for millions of years with no frequent emergence of resistant strains. First,
Dziarski, Roman, Gupta, Dipika
core   +1 more source

Structural determinants for substrate selectivity in guanine deaminase enzymes of the amidohydrolase superfamily.

Biochemistry, 2019
Guanine deaminase is a metabolic enzyme, found in all forms of life, which catalyzes the conversion of guanine to xanthine. Despite the availability of several crystal structures, the molecular determinants of substrate orientation and mechanism remains ...
R. Shek, Tylene Hilaire, Jasper Sim, J. French   +3 more
semanticscholar   +1 more source

Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV

Frontiers in Chemistry
ReAV, the inducible Class-3 L-asparaginase from the nitrogen-fixing symbiotic bacterium Rhizobium etli, is an interesting candidate for optimizing its enzymatic potential for antileukemic applications.
Kinga Pokrywka, Marta Grzechowiak, Joanna Sliwiak, Paulina Worsztynowicz, Joanna I. Loch, Milosz Ruszkowski, Miroslaw Gilski, Miroslaw Gilski, Mariusz Jaskolski, Mariusz Jaskolski   +9 more
doaj   +1 more source

Diverse origins of microbial L-asparaginases and their current miscellaneous applications

Archives of Pharmaceutical Sciences Ain Shams University, 2019
L-asparaginase, also known as amidohydrolase, catalyzes the breakdown of asparagine into aspartic acid and ammonia. Due to its ability to inhibit the biosynthesis of protein lymphoblasts, it is used to treat acute lymphoblastic leukemia (ALL).
Nada A. Abdelrazek, Walid Faisal Elkhatib , Marwa M. Raafat, Mohammad Aboulwafa   +3 more
doaj   +1 more source

Dali server update [PDF]

, 2016
The Dali server (http://ekhidna2.biocenter.helsinki.fi/dali) is a network service for comparing protein structures in 3D. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing ...
Holm, Liisa, Laakso, Laura M.
core   +2 more sources

Molecular cloning and characterization of an amidase from Arabidopsis thaliana capable of converting indole-3-acetamide into the plant growth hormone, indole-3-acetic acid [PDF]

, 2003
Acylamidohydrolases from higher plants have not been characterized or cloned so far. AtAMI1 is the first member of this enzyme family from a higher plant and was identified in the genome of Arabidopsis thaliana based on sequence homology with the ...
Andersson, Ausubel, Bar, Barkan, Bartel, Bradford, Chou, Cravatt, Daniel Neu, Davies, Eckhardt, Elmar W Weiler, Hillebrand, Igoshi, Kawaguchi, Kawaguchi, Klee, Klee, Kobayashi, Kobayashi, Kobayashi, Laemmli, LeClere, Magie, Manulis, McKinney, Sambrook, Saotome, Scharf, Schägger, Stephan Pollmann, Takahashi, Towbin, Vorwerk, Weiler, Yamada, Östin   +36 more
core   +2 more sources

Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium

Advanced Science, EarlyView.
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang, Chunyu Du, Guanyu Zheng, Dahu Ding   +3 more
wiley   +1 more source