[Functional study of amine oxidase copper-containing 1 (AOC1) in lipid metabolism]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiAmine oxidase copper-containing 1 (AOC1) is a key member of copper amine oxidase family, which is responsible for deamination oxidation of histamine and putrescine. In recent years, AOC1 has been reported to be associated with various cancers, with its expression levels significantly elevated in certain cancer cells, suggesting its potential role in ...
Xiang S, Liu S, Li K, Zhao T, Wang X.
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Aokap9 gene knockout contributes to kojic acid synthesis in Aspergillus oryzae [PDF]
Microbial Cell FactoriesBackground Kojic acid, a significant secondary metabolite primarily synthesized by Aspergillus oryzae, has extensive applications across various industries. It is imperative to identify effective gene targets that can enhance kojic acid production and to
Ting Qiu +4 more
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Amine Oxidase, Copper Containing 3 (Aoc3) Knockout Mice Are More Prone to DSS-induced Colitis and Colonic Tumorigenesis. [PDF]
In VivoÖzcan Ö, Akyol Ö, Akyol A.
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Exploring Molecular Oxygen Pathways in Hansenula polymorpha Copper-containing Amine Oxidase [PDF]
Journal of Biological Chemistry, 2007 The accessibility of large substrates to buried enzymatic active sites is dependent upon the utilization of proteinaceous channels. The necessity of these channels in the case of small substrates is questionable because diffusion through the protein matrix is often assumed.
Bryan Johnson +6 more
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The organic functional group in copper-containing amine oxidases
Journal of Biological Chemistry, 1991 Doreen E. Brown +5 more
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Amine oxidase copper-containing 1 (AOC1) is a downstream target gene of the Wilms tumor protein, WT1, during kidney development. [PDF]
J Biol Chem, 2014 Kirschner KM +5 more
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Inactivation of copper‐containing amine oxidases by turnover products [PDF]
European Journal of Biochemistry, 2003 For bovine serum amine oxidase, two different mechanisms of substrate‐induced inactivation have been proposed. One consists of a slow oxidation by H2O2 of a conserved residue in the reduced enzyme after the fast turnover phase [Pietrangeli, P., Nocera, S., Fattibene, P., Wang, X.T., Mondovì, B. & Morpurgo, L. (2000) Biochem. Biophys. Res.
Paola Pietrangeli +4 more
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Transient kinetics of copper-containing lentil (Lens culinaris) seedling amine oxidase [PDF]
Biochemical Journal, 1985 The reaction between lentil (Lens culinaris) seedling amine oxidase and its chromogenic substrate, p-dimethylaminomethylbenzylamine, has been studied by the stopped-flow technique. Upon being mixed with substrate in the absence of oxygen, the enzyme is bleached in a complex kinetic process.
Andrea Bellelli +5 more
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Inhibition of copper-containing amine oxidase by oximes.
Chemical and Pharmaceutical Bulletin, 1988 The inhibitory effects of twelve oxime compounds on the activity of bovine serum monoamine oxidase (copper-containing amine oxidase, E.C. 1.4.3.6) were assayed in vitro. The most potent inhibitor among the compounds examined was 2-butanone oxime, of which the 50% inhibiting concentration in the reaction mixture was 7×10-6 M.
Atsushi Hiraoka +5 more
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Interaction of Pig Kidney and Lentil Seedling Copper-Containing Amine Oxidases with Guanidinium Compounds [PDF]
Journal of Enzyme Inhibition, 1999 The effect of guanidinium compounds on the catalytic mechanism of pig kidney and lentil seedling amine oxidases has been investigated by polarographic techniques and spectroscopy. Guanidine does not inhibit the lentil enzyme and is a weak inhibitor for pig kidney amine oxidase (K(i) =1 mM), whereas aminoguanidine is an irreversible inhibitor of both ...
Alessandra Padiglia +6 more
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