Aliphatic amines, including methylamine, are air-pollutants, due to their intensive use in industry and the natural degradation of proteins, amino acids, and other nitrogen-containing compounds in biological samples.
Sasi Sigawi+5 more
doaj +1 more source
Background The detection of selective traits in different populations can not only reveal current mechanisms of artificial selection for breeding, but also provide new insights into phenotypic variation in new varieties and the search for genes ...
Huibin Shi+6 more
doaj +1 more source
Polymer coated cerium oxide nanoparticles as oxidoreductase-like catalysts [PDF]
Cerium oxide nanoparticles have been shown to mimic oxidoreductase enzymes by catalyzing the decomposition of organic substrates and reactive oxygen species. This mimicry can be found in superoxide radicals and hydrogen peroxides, harmful molecules produced in oxidative stress asso-ciated diseases.
arxiv +1 more source
Kinetics of proton pumping in cytochrome c oxidase [PDF]
We propose a simple model of cytochrome c oxidase, including four redox centers and four protonable sites, to study the time evolution of electrostatically coupled electron and proton transfers initiated by the injection of a single electron into the enzyme.
arxiv +1 more source
Portosystemic hepatic encephalopathy model shows reversal learning impairment and dysfunction of neural activity in the prefrontal cortex and regions involved in motivated behavior [PDF]
Hepatic encephalopathy is a neurological complication that affects attention and memory. Experimental animal models have been used to study hepatic Encephalopathy, the most frequent being the portacaval shunt. In order to determine learning impairment and brain functional alterations in this model, we assessed reversal learning and neural metabolic ...
arxiv +1 more source
The two most prevalent subtypes of epithelial ovarian carcinoma (EOC) are ovarian clear cell carcinoma (OCCC) and high-grade serous ovarian carcinoma (HGSC).
Dan Guo+22 more
doaj +1 more source
Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia
Objective To determine the influence of ultrasound/microbubble-mediated miR-424-5p delivery on trophoblast cellsĀ and the underlying mechanism. Methods Blood pressure and 24-h proteinuria of patients with preeclampsia (PE) were measured as well as the ...
Xudong Wang+6 more
doaj +1 more source
Mathematical Model for Chemical Reactions in Electrolyte Applied to Cytochrome $c$ Oxidase: an Electro-osmotic Approach [PDF]
A mathematical model for chemical reactions in electrolytes is developed using an Energy variational method consistent with classical thermodynamics. Electrostatics and chemical reactions are included in properly defined energetic and dissipative functionals.
arxiv
Proteomic analysis of premature umbilical cord blood and its relationship with bronchopulmonary dysplasia. [PDF]
Background Bronchopulmonary dysplasia (BPD) frequently occurs in preterm infants, causing significantly impaired lung function and increased mortality rates.
Chen J+6 more
europepmc +2 more sources
Extended Linear Response for Bioanalytical Applications Using Multiple Enzymes [PDF]
We develop a framework for optimizing a novel approach to extending the linear range of bioanalytical systems and biosensors by utilizing two enzymes with different kinetic responses to the input chemical as their substrate. Data for the flow-injection amperometric system devised for detection of lysine based on the function of L-Lysine-alpha-Oxidase ...
arxiv +1 more source