Results 51 to 60 of about 480,427 (337)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

2-((Pyren-1-ylmethylamino)methyl)quinolin-8-ol

Molbank, 2010
A new fluorescent compound L1 derived from 1-pyrenemethylamine hydrochloride (A) has been synthesized by classical Schiff-base reaction between (A) and 8-hydroxyquinoline-2-carbaldehyde (B) followed by a chemical reduction with NaBH4.
Carlos Lodeiro, Javier Fernández-Lodeiro, Cristina Nuñez, José Luis Capelo   +3 more
doaj   +1 more source

Acetylation of alcohols and amines catalyzed by onion peel ash under a base- and solvent-free condition [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2020
This manuscript describes a facile and environmentally benign protocol for the acetylation of various alcohol and amines catalyzed by onion peel ash under a base- and solvent-free condition. Various acetates were successfully prepared from the alcohols
Poh Wai Chia, Poh Seng Chee, Noor Wini Mazla, Fu Siong Julius Yong, Mohd Zul Helmi Rozaini, Su-Yin Kan   +5 more
doaj   +1 more source

The effect of fluorine-containing inhibitors of corrosion of copper in atmospheric conditions [PDF]

, 2016
The effect of fluorine-containing inhibitors of corrosion of copper in atmospheric conditions was studied by method of removing anodic polarization curves and corrosion of full-scale tests.
Ivanov, M. G., Mokrushin, V. S., Nechaev, A. V., Ostroukhova, O. I.   +3 more
core   +2 more sources

Chemical modeling for predicting the abundances of certain aldimines and amines in hot cores

, 2021
We consider six isomeric groups (CH3N, CH5N, C2H5N, C2H7N, C3H7N and C3H9N) to review the presence of amines and aldimines within the interstellar medium (ISM). Each of these groups contains at least one aldimine or amine.
Bhat, Bratati, Chakrabarti, Sandip K., Das, Ankan, Etim, Emmanuel E., Gorai, Prasanta, Sil, Milan   +5 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Spectroscopic and Quantum Chemical Evidence of Amine–CO₂ and Alcohol–CO₂ Interactions: Confirming an Intriguing Affinity of CO₂ to Monoethanolamine (MEA)

Molecules
A recent broadband rotational spectroscopic investigation of the cross-association mechanisms of CO2 with monoethanolamine (MEA) in molecular beams [F. Xie et al., Angew. Chem. Int. Ed., 2023, 62, e202218539] revealed an intriguing affinity of CO2 to the
Sahar Hafizi Yazdabadi, Dmytro Mihrin, Karen Louise Feilberg, René Wugt Larsen   +3 more
doaj   +1 more source

Automated analysis of oxidative metabolites [PDF]

, 1974
An automated system for the study of drug metabolism is described. The system monitors the oxidative metabolites of aromatic amines and of compounds which produce formaldehyde on oxidative dealkylation.
Furner, R. L.
core   +1 more source

A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines [PDF]

, 2013
4-Substituted 1-bromoisoquinolin-3-amines were subjected to Suzuki coupling with o-nitrophenylboronic acid to yield 1-(2-nitrophenyl) isoquinolinamines, which participated in Cadogan cyclization with triethyl phosphite under microwave irradiation in a ...
Balog, József, Hajós, György, Riedl, Zsuzsanna   +2 more
core   +1 more source