Results 11 to 20 of about 7,026,669 (342)

Brain amino acid sensing for organismal amino acid homeostasis [PDF]

open access: yesOpen Biology
Amino acids are essential for normal physiological functions, and disruptions in their circulating concentrations are implicated in the pathophysiology of various diseases.
Anthony H. Tsang   +2 more
doaj   +2 more sources

Emerging Insights into the Relationship Between Amino Acid Metabolism and Diabetic Cardiomyopathy [PDF]

open access: yesBiomolecules
Diabetes mellitus (DM) is a complex global pandemic that frequently leads to multiple complications. Diabetic cardiomyopathy (DCM) is the primary cause of heart failure in patients with type 1 and 2 diabetes and is fundamentally characterized by ...
Yi Wen   +4 more
doaj   +2 more sources

Quinone-amino acid conjugates targeting Leishmania amino acid transporters. [PDF]

open access: yesPLoS ONE, 2014
The aim of the present study was to investigate the feasibility of targeting Leishmania transporters via appropriately designed chemical probes. Leishmania donovani, the parasite that causes visceral leishmaniasis, is auxotrophic for arginine and lysine ...
Federica Prati   +6 more
doaj   +1 more source

Unnatural Amino Acid: 4-Aminopyrazolonyl Amino Acid Comprising Tri-Peptides Forms Organogel With Co-Solvent (EtOAc:Hexane)

open access: yesFrontiers in Chemistry, 2022
Ampyrone is an amino-functionalized heterocyclic pyrazolone derivative that possesses therapeutic values such as analgesic, anti-inflammatory, and antipyretics.
Amarnath Bollu   +9 more
doaj   +1 more source

Photosynthesis of amino acids [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 1964
Abstract Methods have been developed for performing dual tracer experiments with 15 N and 14 C on the photosynthesis and biosynthesis of amino acids in Chlorella pyrenoidosa . These methods involved the development of apparatus for maintaining algae in a condition of steady-state photosynthesis, including amino acid synthesis, and of adding ...
Bassham, J.A., Kirk, Martha.
openaire   +3 more sources

Amino acid impact factor. [PDF]

open access: yesPLoS ONE, 2018
Amino acid mutations in proteins are random and those mutations which are beneficial or neutral survive during the course of evolution. Conservation or co-evolution analyses are performed on the multiple sequence alignment of homologous proteins to ...
C K Sruthi, Meher Prakash
doaj   +1 more source

SIFT: predicting amino acid changes that affect protein function

open access: yesNucleic Acids Res., 2003
Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding regions. Each substitution has the potential to affect protein function. SIFT (Sorting Intolerant From Tolerant) is a program
P. Ng, S. Henikoff
semanticscholar   +1 more source

Incorporation of Unnatural Amino Acid into Antibody Fragment for Creating a Stable Antibody Drug Conjugate

open access: yesIndonesian Journal of Pharmacy, 2021
The traditional chemotherapy drug has been used as a standard cancer treatment, however it has resulted a modest survival benefit and damaged non-cancerous cells.
Andri Wardiana   +3 more
doaj   +1 more source

Amino acid substitution matrices from protein blocks.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1992
Methods for alignment of protein sequences typically measure similarity by using a substitution matrix with scores for all possible exchanges of one amino acid with another.
S. Henikoff, J. Henikoff
semanticscholar   +1 more source

Principal Component Analysis and Cluster Analysis for Evaluating Amino Acid of Different Table Grapes (Vitis vinifera L.) Varieties

open access: yesShipin gongye ke-ji, 2022
Objective: In order to find out the differences in the content, composition characteristics and nutritional value of amino acid in different fresh grape varieties.
Sun’an YAN   +4 more
doaj   +1 more source

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