Results 11 to 20 of about 8,614,620 (399)
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor [PDF]
Nature Communications, 2016 Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Abigail S. Krall +4 more
semanticscholar +3 more sources
Frontiers in Plant Science, 2020 Staple crops in human and livestock diets suffer from deficiencies in certain “essential” amino acids including methionine. With the goal of increasing methionine in rice seed, we generated a pair of “Push × Pull” double transgenic lines, each containing
Sarah J. Whitcomb +8 more
doaj +1 more source
Electrospinning and Post-Spun Chain Conformations of Synthetic, Hydrophobic Poly(α-amino acid)s. [PDF]
, 2020 Electrospinning and post-spun conformations of hydrophobic poly(α-amino acid)s are described in this study. The poly(α-amino acid)s, poly(Gly), poly(L-Ala), poly(L-Val), and poly(L-Leu) were synthesized via corresponding N-carboxy-a-amino acid anhydrides.
Devarayan, Kesavan +4 more
core +1 more source
Experimental & Molecular Medicine, 2020 AbstractOver 90 years ago, Otto Warburg’s seminal discovery of aerobic glycolysis established metabolic reprogramming as one of the first distinguishing characteristics of cancer1. The field of cancer metabolism subsequently revealed additional metabolic alterations in cancer by focusing on central carbon metabolism, including the citric acid cycle and
Elizabeth L. Lieu +3 more
openaire +4 more sources
Quinone-amino acid conjugates targeting Leishmania amino acid transporters. [PDF]
PLoS ONE, 2014 The aim of the present study was to investigate the feasibility of targeting Leishmania transporters via appropriately designed chemical probes. Leishmania donovani, the parasite that causes visceral leishmaniasis, is auxotrophic for arginine and lysine ...
Federica Prati +6 more
doaj +1 more source
Frontiers in Chemistry, 2022 Ampyrone is an amino-functionalized heterocyclic pyrazolone derivative that possesses therapeutic values such as analgesic, anti-inflammatory, and antipyretics.
Amarnath Bollu +9 more
doaj +1 more source
Photosynthesis of amino acids [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 1964 Abstract Methods have been developed for performing dual tracer experiments with 15 N and 14 C on the photosynthesis and biosynthesis of amino acids in Chlorella pyrenoidosa . These methods involved the development of apparatus for maintaining algae in a condition of steady-state photosynthesis, including amino acid synthesis, and of adding ...
Bassham, J.A., Kirk, Martha.
openaire +3 more sources
Impaired nutrient signaling and body weight control in a Na⁺ neutral amino acid cotransporter (Slc6a19)-deficient mouse [PDF]
, 2015 Amino acid uptake in the intestine and kidney is mediated by a variety of amino acid transporters. To understand the role of epithelial neutral amino acid uptake in whole body homeostasis, we analyzed mice lacking the apical broad-spectrum neutral (0 ...
Bailey, Charles G. +8 more
core +1 more source
Amino acid impact factor. [PDF]
PLoS ONE, 2018 Amino acid mutations in proteins are random and those mutations which are beneficial or neutral survive during the course of evolution. Conservation or co-evolution analyses are performed on the multiple sequence alignment of homologous proteins to ...
C K Sruthi, Meher Prakash
doaj +1 more source
Indonesian Journal of Pharmacy, 2021 The traditional chemotherapy drug has been used as a standard cancer treatment, however it has resulted a modest survival benefit and damaged non-cancerous cells.
Andri Wardiana +3 more
doaj +1 more source