Results 51 to 60 of about 7,026,669 (342)

Methionine to cystine ratio in the total sulfur amino acid requirements and sulfur amino acid metabolism using labelled amino acid approach for broilers

open access: yesBMC Veterinary Research, 2018
Background Assuming that part of Methionine (Met) is converted into Cystine (Cys), but ignoring the rates with which such phenomenon occurs may lead to an excessive supply of Met in poultry diets.
Letícia G. Pacheco   +6 more
doaj   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Amino Acid Transporters on Amino Acid Absorption, Transport and Distribution in Crops

open access: yesHorticulturae
Amino acid transporters mediate amino acid transport within and between cells and are the main mediators of nitrogen distribution in plants, which is crucial for maintaining plant growth and development.
Lu Liu   +6 more
doaj   +1 more source

Variation among arthropod taxa in the amino acid content of exoskeleton and digestible tissue

open access: yesEcology and Evolution, 2023
Arthropod consumption provides amino acids to invertebrates and vertebrates alike, but not all amino acids in arthropods may be digestible as some are bound in the exoskeleton.
Jamie T. Reeves   +5 more
doaj   +1 more source

Role of amino acid transporters in amino acid sensing [PDF]

open access: yesThe American Journal of Clinical Nutrition, 2014
Amino acid (AA) transporters may act as sensors, as well as carriers, of tissue nutrient supplies. This review considers recent advances in our understanding of the AA-sensing functions of AA transporters in both epithelial and nonepithelial cells.
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Impaired amino acid uptake leads to global metabolic imbalance of Candida albicans biofilms

open access: yesnpj Biofilms and Microbiomes, 2022
Candida albicans biofilm maturation is accompanied by enhanced expression of amino acid acquisition genes. Three state-of-the-art omics techniques were applied to detail the importance of active amino acid uptake during biofilm development.
Bettina Böttcher   +7 more
doaj   +1 more source

Catalytic amino acid production from biomass-derived intermediates

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Today, amino acids are primarily manufactured via microbial cultivation processes, which are costly, are time consuming, and require extensive separations processes.
Weiping Deng   +14 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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