Results 51 to 60 of about 10,650 (286)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Ni(II)-PPP Complexes: From the Hydroamination of Activated Olefins to the Synthesis of ?-Amino Acids

CHIMIA, 2004
Complexes of the type [Ni(PPP)(solvent)]X2 containing ferrocenyl tridentate ligands have been prepared and used as catalysts in the asymmetric hydroamination of activated olefins (i.e. bearing an electron-withdrawing group).
Luca Fadini, Antonio Togni
doaj   +1 more source

Room Temperature Ionic Liquids from 20 Natural Amino Acids

, 2016
We first succeeded in synthesizing ionic liquids from 20 natural amino acids. Amino acid ionic liquids dissolved native amino acids, despite water-free conditions.
Masahiro Yoshizawa (2691652), Kenta Fukumoto (2691655), Hiroyuki Ohno (615573)   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Characterization of the acidity and basicity of green solvents by NMR techniques

Magnetic Resonance Letters, 2021
The acidity and basicity of the solvents can influence the reaction outcome notably, and hence the precise measurement of pH is important for reaction.
Kemeng Shi, Christian Marcus Pedersen, Hui Chang, Jing Shi, Yingxiong Wang, Yan Qiao   +5 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Theoretical Enthalpies of Formation of [AA]X and [AAE]X Type Amino Acid Ionic Liquids

, 2016
The theoretical enthalpies of formation of 108 [AA]­X and [AAE]­X type amino acid ionic liquids composed of 12 amino acid cations (Gly+, GlyC1+, Ala+, AlaC1+, Pro+, ProC1+, Phe+, PheC1+, Val+, ValC1+, Leu+, LeuC1+) with 9 different anions (Cl–, BF4–, PF6–
Changwei Hu (1281810), Ming Huang (301457), Lin-Lin Dong (1960246), Ling He (282204), Guo-Hong Tao (587605)   +4 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Synthesis and evaluation of amino acid ionic liquid for enhanced oil recovery: experimental and modeling simulation studies

Scientific Reports
Recovering the remaining oil after primary and secondary extraction methods poses a significant challenge. Enhanced oil recovery (EOR) techniques, which involve injecting fluids into reservoirs, aim to increase recovery rates.
E. M. Mansour, R. Hosny, Ammona S. Mohamed, Fatma M. Abdelhafiz   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source