Results 111 to 120 of about 4,987,268 (293)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Amino acid fluxes from moored sediment traps

, 2003
Amino acid fluxes from moored sediment ...
Cindy Lee (7887515), Lee, Cindy
core   +1 more source

Nutritional composition analysis and quality evaluation of muscle in Wallago attu in Lancang River

Siliao yanjiu, 2023
The experiment was to analyze the nutritional components of muscle of Wallago attu. The nutritional composition, amino acid and fatty acid composition of juvenile and adult catfish were analyzed by biochemical methods to evaluate their nutritional ...
WANG Chong
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

An evaluation integrating in vivo digestibility and amino acid analysis of protein nutritional quality of cultured meat

Zhongguo shipin weisheng zazhi
ObjectiveTo systematically evaluate the protein nutritional quality of cultured meat， clarify its digestibility， absorption efficiency and amino acid matching degree， and provide a scientific basis for the development and application of cultured meat as ...
TIAN Weining, OU Tong, SHAO Yiming, HONG Xinyu, YONG Ling, ZHANG Weichunbai, SONG Yan, LIU Zhaoping   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Amino acid compositions from plankton tow collections

, 2003
Amino acid compositions from plankton tow ...
Cindy Lee (7887515), Lee, Cindy
core   +1 more source

Brief Research Report: Estimation of the Protein Digestibility-Corrected Amino Acid Score of Defatted Walnuts. [PDF]

Front Nutr, 2021
Lackey KA, Fleming SA.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Amino acid composition of wild yam (Dioscorea spp.) [PDF]

Food Research, 2019
Doss, A. , Tresina, P.S. , Mohan, V.R.
doaj   +1 more source