Results 121 to 130 of about 4,987,268 (293)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Comparative study on growth and muscle composition of Ctenopharyngodon idella under two aquaculture patterns

open access: yesSiliao yanjiu, 2021
The experiment compared the growth and muscle composition of Ctenopharyngodon idella cultured in recirculating aquaculture mode and pond aquaculture mode.
Jian-yong HU   +5 more
doaj  

Quality changes of different varieties of pepper during natural fermentation process [PDF]

open access: yesZhongguo niangzao
Chopped pepper was prepared with Xiaomila and Erjingtiao as raw materials, the changes of physiochemical indexes and sensory quality of chopped pepper during natural fermentation process was analyzed, and the effects of fermentation time and pepper ...
ZHENG Rong, HE Xufeng, XIONG Shuang, HU Lu, YI Liangjian, HUANG Wenping, LONG Chao, HUANG Xiaolan
doaj   +1 more source

True ileal amino acid digestibility and digestible amino acid scores (DIAASs) of the cruciferin and napin fractions of rapeseed: Impact of processing

open access: yesFood Chemistry
Processes are being developed to exploit proteins from the residue of rapeseed oil extraction. Two main fractions of proteins can be purified: cruciferin and napin. The present work was carried out to characterize the nutritional quality of these fractions, while exploring the effect of the extraction conditions (neutral or acid), and that of the post ...
Kapel, Romain   +10 more
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Nutrient Composition Analysis in Quasipaa spinosa Eggs

open access: yesJournal of Food Quality
The objective of this study was to determine the nutrient composition of Quasipaa spinosa eggs and evaluate their nutritional value. The findings from this study can be utilized to propose recommendations for further development of Q. spinosa.
Han Li   +5 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Evidence for two pharmacologically distinct populations of glutamate-activated first order interneurons in a vertebrate spinal cord.

open access: yes, 1987
p. 357-360.The Atlantic stingray, Dasyatis sabina, is being employed as a simple vertebrate model for studying spinal cord circuitry. Current investigations are aimed at determining the role of excitatory amino acids in the production of spinal reflexes.
Leonard, R.B., Gannon, R.L.
core   +1 more source

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