Results 1 to 10 of about 2,757,435 (387)

Predicting the functional effect of amino acid substitutions and indels. [PDF]

open access: yesPLoS ONE, 2012
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi   +4 more
doaj   +2 more sources

THE AMINO ACID SEQUENCE OF HYPERTENSIN II [PDF]

open access: bronzeThe Journal of Experimental Medicine, 1956
The amino acid sequence of horse hypertensin II has been determined by the use of chymotrypsin, the fluorodinitrobenzene method, and stepwise phenylisothiocyanate degradation. The results indicate that the amino acids of hypertensin II are arranged in the following order: asp-arg-val-tyr-iso-hist-pro-phe.
Leonard T. Skeggs   +4 more
openalex   +5 more sources

SSE: a nucleotide and amino acid sequence analysis platform

open access: yesBMC Research Notes, 2012
Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
doaj   +2 more sources

The Amino Acid Sequence of Ribonuclease T1 [PDF]

open access: hybridJournal of Biological Chemistry, 1965
into other products. Glucoand galactocerebrosides, and ceramide trisaccharide, showed no activity (i.e. less than 300 cpm soluble in chloroform-methanol). Chloroform-methanolsoluble products were obtained with the following lipids: 4900 cpm with hematoside at 0.1 pmole per incubation mixture, and 7900 at 0.2 pmole; ceramide disaccharide, 720 cpm at 0.1
Kenji Takahashi
openalex   +3 more sources

Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]

open access: yesBMC Bioinformatics, 2022
Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson   +3 more
doaj   +2 more sources

THE AMINO ACID SEQUENCE OF BOVINE CARBOXYPEPTIDASE A [PDF]

open access: greenProceedings of the National Academy of Sciences, 1969
The amino acid sequence of the four fragments produced by treatment of bovine carboxypeptidase A with cyanogen bromide has been completed. The alignment of these fragments, previously established by peptic digest of the whole protein, allows for the description of the complete primary structure of the molecule.
Ralph Bradshaw   +3 more
openalex   +4 more sources

Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]

open access: yesJisuanji kexue, 2022
Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj   +1 more source

Multiple rereads of single proteins at single–amino acid resolution using nanopores

open access: yesScience, 2021
Description Reading amino acids by nanopore Nanopore technology enables sensing of minute chemical changes at the single-molecule level by detecting differences in an ion current as molecules are drawn through a membrane-embedded pore. The sensitivity is
H. Brinkerhoff   +4 more
semanticscholar   +1 more source

Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]

open access: yesPeerJ, 2020
Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó   +5 more
doaj   +2 more sources

Amino acid sequence of bacteriorhodopsin. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1979
The complete primary structure of the purple membrane protein bacteriorhodopsin, which contains 248 amino acid residues, has been determined. Methods used for separation of the hydrophobic fragments included gel permeation and reverse-phase high-pressure liquid chromatography in organic solvents.
H G Khorana   +6 more
openaire   +3 more sources

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