Results 1 to 10 of about 2,809,935 (342)
aaHash: recursive amino acid sequence hashing. [PDF]
Bioinform Adv, 2023 AbstractMotivationK-mer hashing is a common operation in many foundational bioinformatics problems. However, generic string hashing algorithms are not optimized for this application. Strings in bioinformatics use specific alphabets, a trait leveraged for nucleic acid sequences in earlier work.
Wong J +4 more
europepmc +4 more sources
Predicting the functional effect of amino acid substitutions and indels.
PLoS ONE, 2012 As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi +4 more
doaj +2 more sources
SSE: a nucleotide and amino acid sequence analysis platform
BMC Research Notes, 2012 Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
doaj +2 more sources
Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]
BMC Bioinformatics, 2022 Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson +3 more
doaj +2 more sources
Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]
Jisuanji kexue, 2022 Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj +1 more source
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]
PeerJ, 2020 Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó +5 more
doaj +2 more sources
Multiple rereads of single proteins at single–amino acid resolution using nanopores
Science, 2021 Description Reading amino acids by nanopore Nanopore technology enables sensing of minute chemical changes at the single-molecule level by detecting differences in an ion current as molecules are drawn through a membrane-embedded pore. The sensitivity is
H. Brinkerhoff +4 more
semanticscholar +1 more source
Amino acid sequence of rabbit apolipoprotein E.
Journal of Lipid Research, 1991 The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee +6 more
doaj +1 more source
An Alternative Model of Amino Acid Replacement [PDF]
, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
core +3 more sources