Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]
BMC Bioinformatics, 2022 Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson +3 more
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Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]
Jisuanji kexue, 2022 Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
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Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]
PeerJ, 2020 Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó +5 more
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Amino acid sequence of bacteriorhodopsin. [PDF]
Proceedings of the National Academy of Sciences, 1979 The complete primary structure of the purple membrane protein bacteriorhodopsin, which contains 248 amino acid residues, has been determined. Methods used for separation of the hydrophobic fragments included gel permeation and reverse-phase high-pressure liquid chromatography in organic solvents.
H G Khorana +6 more
openaire +3 more sources
Amino acid sequence of rabbit apolipoprotein E.
Journal of Lipid Research, 1991 The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee +6 more
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An Alternative Model of Amino Acid Replacement [PDF]
, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
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Amino acid sequence alignment of vertebrate CAPN3/calpain-3/p94
Data in Brief, 2015 CAPN3 is a calpain superfamily member that is predominantly expressed in skeletal muscle. So far, clear CAPN3 orthologs were found only in vertebrates.
Yasuko Ono, Hiroyuki Sorimachi
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Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]
, 2012 At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P. +4 more
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Isolation and characterization of cDNA clones corresponding to two different human apoC-III alleles.
Journal of Lipid Research, 1985 We have recently reported that the human apolipoprotein A-I (apoA-I) and apolipoprotein C-III (apoC-III) genes are physically linked and that the presence of a DNA insertion in the apoA-I gene is correlated with apoA-I-apoC-III deficiency in patients ...
S K Karathanasis +2 more
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Predicting the functional effect of amino acid substitutions and indels. [PDF]
PLoS ONE, 2012 As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi +4 more
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