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Predicting the functional effect of amino acid substitutions and indels. [PDF]
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi+4 more
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THE AMINO ACID SEQUENCE OF HYPERTENSIN II [PDF]
The amino acid sequence of horse hypertensin II has been determined by the use of chymotrypsin, the fluorodinitrobenzene method, and stepwise phenylisothiocyanate degradation. The results indicate that the amino acids of hypertensin II are arranged in the following order: asp-arg-val-tyr-iso-hist-pro-phe.
Leonard T. Skeggs+4 more
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SSE: a nucleotide and amino acid sequence analysis platform
Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
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The Amino Acid Sequence of Ribonuclease T1 [PDF]
into other products. Glucoand galactocerebrosides, and ceramide trisaccharide, showed no activity (i.e. less than 300 cpm soluble in chloroform-methanol). Chloroform-methanolsoluble products were obtained with the following lipids: 4900 cpm with hematoside at 0.1 pmole per incubation mixture, and 7900 at 0.2 pmole; ceramide disaccharide, 720 cpm at 0.1
Kenji Takahashi
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Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]
Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson+3 more
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THE AMINO ACID SEQUENCE OF BOVINE CARBOXYPEPTIDASE A [PDF]
The amino acid sequence of the four fragments produced by treatment of bovine carboxypeptidase A with cyanogen bromide has been completed. The alignment of these fragments, previously established by peptic digest of the whole protein, allows for the description of the complete primary structure of the molecule.
Ralph Bradshaw+3 more
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Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]
Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
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Multiple rereads of single proteins at single–amino acid resolution using nanopores
Description Reading amino acids by nanopore Nanopore technology enables sensing of minute chemical changes at the single-molecule level by detecting differences in an ion current as molecules are drawn through a membrane-embedded pore. The sensitivity is
H. Brinkerhoff+4 more
semanticscholar +1 more source
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]
Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó+5 more
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Amino acid sequence of bacteriorhodopsin. [PDF]
The complete primary structure of the purple membrane protein bacteriorhodopsin, which contains 248 amino acid residues, has been determined. Methods used for separation of the hydrophobic fragments included gel permeation and reverse-phase high-pressure liquid chromatography in organic solvents.
H G Khorana+6 more
openaire +3 more sources