Results 1 to 10 of about 1,607,008 (329)

Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]

open access: yesBMC Bioinformatics, 2022
Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson   +3 more
doaj   +2 more sources

Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]

open access: yesJisuanji kexue, 2022
Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj   +1 more source

Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]

open access: yesPeerJ, 2020
Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó   +5 more
doaj   +2 more sources

An Alternative Model of Amino Acid Replacement [PDF]

open access: yes, 2004
The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul   +27 more
core   +3 more sources

Amino acid sequence alignment of vertebrate CAPN3/calpain-3/p94

open access: yesData in Brief, 2015
CAPN3 is a calpain superfamily member that is predominantly expressed in skeletal muscle. So far, clear CAPN3 orthologs were found only in vertebrates.
Yasuko Ono, Hiroyuki Sorimachi
doaj   +1 more source

Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]

open access: yes, 2012
At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P.   +4 more
core   +1 more source

Predicting the functional effect of amino acid substitutions and indels. [PDF]

open access: yesPLoS ONE, 2012
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi   +4 more
doaj   +1 more source

Amino Acid Sequences of Lactoferrin from Red Deer (Cervus elaphus) Milk and Antimicrobial Activity of Its Derived Peptides Lactoferricin and Lactoferrampin

open access: yesFoods, 2021
Although the bioactivities of bovine lactoferrin have been extensively investigated, little is known about deer milk lactoferrin bioactivity and its amino acid sequence.
Ye Wang   +4 more
doaj   +1 more source

Site-Directed Mutagenesis and Site-Specific Binding Analysis of Calmodulin (CaM) [PDF]

open access: yes, 2017
Calcium signaling is a major regulatory system in cells and a crucial part of cell biology. An important element in the decoding of intracellular calcium concentration into downstream processes is the ubiquitous and highly conserved calcium binding ...
Dokic, Yelena
core   +1 more source

Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]

open access: yes, 2003
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W.   +2 more
core   +4 more sources

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