Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]
Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson +3 more
doaj +2 more sources
The Photoprotective Protein PsbS from Green Microalga Lobosphaera incisa: The Amino Acid Sequence, 3D Structure and Probable pH-Sensitive Residues. [PDF]
Ptushenko VV, Knorre DD, Glagoleva ES.
europepmc +3 more sources
Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]
Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj +1 more source
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]
Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó +5 more
doaj +2 more sources
Amino acid sequence of rabbit apolipoprotein E.
The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee +6 more
doaj +1 more source
An Alternative Model of Amino Acid Replacement [PDF]
The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
core +3 more sources
Amino acid sequence alignment of vertebrate CAPN3/calpain-3/p94
CAPN3 is a calpain superfamily member that is predominantly expressed in skeletal muscle. So far, clear CAPN3 orthologs were found only in vertebrates.
Yasuko Ono, Hiroyuki Sorimachi
doaj +1 more source
Amino acid metabolism conflicts with protein diversity [PDF]
The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine.
Alonso, Leonardo G. +6 more
core +4 more sources
Isolation and characterization of cDNA clones corresponding to two different human apoC-III alleles.
We have recently reported that the human apolipoprotein A-I (apoA-I) and apolipoprotein C-III (apoC-III) genes are physically linked and that the presence of a DNA insertion in the apoA-I gene is correlated with apoA-I-apoC-III deficiency in patients ...
S K Karathanasis +2 more
doaj +1 more source
Predicting the functional effect of amino acid substitutions and indels. [PDF]
As next-generation sequencing projects generate massive genome-wide sequence variation data, bioinformatics tools are being developed to provide computational predictions on the functional effects of sequence variations and narrow down the search of ...
Yongwook Choi +4 more
doaj +1 more source

