An Alternative Model of Amino Acid Replacement [PDF]
Bioinformatics 2005 21(7):975-980, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
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Amino acid metabolism conflicts with protein diversity [PDF]
arXiv, 2014 The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine.
Alonso, Leonardo G. +6 more
core +5 more sources
Reading the three-dimensional structure of a protein from its amino acid sequence [PDF]
arXiv, 2000 While all the information required for the folding of a protein is contained in its amino acid sequence, one has not yet learnt how to extract this information so as to predict the detailed, biological active, three-dimensional structure of a protein ...
Broglia, R. A., Tiana, G.
core +2 more sources
Organizing the bacterial annotation space with amino acid sequence embeddings [PDF]
BMC Bioinformatics, 2022 Background Due to the ever-expanding gap between the number of proteins being discovered and their functional characterization, protein function inference remains a fundamental challenge in computational biology.
Susanna R. Grigson +3 more
doaj +2 more sources
The association between HIV-1 Tat and Vif amino acid sequence variation, inflammation and Trp-Kyn metabolism: an exploratory investigation [PDF]
BMC Infectious DiseasesBackground HIV-1 has well-established mechanisms to disrupt essential pathways in people with HIV, such as inflammation and metabolism. Moreover, diversity of the amino acid sequences in fundamental HIV-1 proteins including Tat and Vif, have been linked ...
Monray E. Williams +3 more
doaj +2 more sources
Protein Solubility Prediction Based on Sequence Feature Fusion [PDF]
Jisuanji kexue, 2022 Protein solubility plays an important role in the research of drug design.Traditional biological experiments of detecting protein solubility are time-consuming and laborious.Identifying protein solubility based on computational methods has become an ...
NIU Fu-sheng, GUO Yan-bu, LI Wei-hua, LIU Wen-yang
doaj +1 more source
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus [PDF]
PeerJ, 2020 Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico.
José M. Viader-Salvadó +5 more
doaj +2 more sources
Word decoding of protein amino Acid sequences with availability analysis: a linguistic approach. [PDF]
PLoS ONE, 2012 The amino acid sequences of proteins determine their three-dimensional structures and functions. However, how sequence information is related to structures and functions is still enigmatic.
Kenta Motomura +5 more
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Amino acid sequence alignment of vertebrate CAPN3/calpain-3/p94
Data in Brief, 2015 CAPN3 is a calpain superfamily member that is predominantly expressed in skeletal muscle. So far, clear CAPN3 orthologs were found only in vertebrates.
Yasuko Ono, Hiroyuki Sorimachi
doaj +1 more source
Foods, 2021 Although the bioactivities of bovine lactoferrin have been extensively investigated, little is known about deer milk lactoferrin bioactivity and its amino acid sequence.
Ye Wang +4 more
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