Results 1 to 10 of about 223,664 (123)
Characterization of blood-brain barrier L-arginine uptake using in situ brain perfusions in a female mouse model [PDF]
Fluids and Barriers of the CNSBackground L-arginine is a critical determinant of central nervous system (CNS) function through nitric oxide (NO) production. Its uptake from plasma into brain is dependent on carrier-mediated transport across the blood-brain barrier (BBB).
Olivia C. Milam +7 more
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Identification of transport systems involved in eflornithine delivery across the blood-brain barrier
Frontiers in Drug Delivery, 2023 Human African Trypanosomiasis (HAT) is a neglected parasitic disease that continues to persist in sub-Saharan Africa. It is fatal if untreated. The first stage of the disease is associated with the presence of the parasite in the periphery and the second
Christopher P. Watson +2 more
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Cells, 2021 L-Arginine, a semi-essential amino acid, was shown to delay dysfunction of motor neurons and to prolong the lifespan, upon analysis of transgenic mouse models of amyotrophic lateral sclerosis (ALS).
Sana Latif, Young-Sook Kang
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Frontiers in Bioengineering and Biotechnology, 2023 We investigated the optimum co-culture ratio with the highest biological nitrogen removal rate, revealing that chemical oxygen demand, total nitrogen (TN), and ammoniacal nitrogen (NH3-N) removal was increased in the Chlorella pyrenoidosa and Yarrowia ...
Yuming Zhong +6 more
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Systems biology of the qa gene cluster in Neurospora crassa. [PDF]
PLoS ONE, 2011 An ensemble of genetic networks that describe how the model fungal system, Neurospora crassa, utilizes quinic acid (QA) as a sole carbon source has been identified previously.
Xiaojia Tang +10 more
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L-arginine attenuates Interleukin-1β (IL-1β) induced Nuclear Factor Kappa-Beta (NF-κB) activation in Caco-2 cells. [PDF]
PLoS ONE, 2017 BACKGROUND:Specific nutrients like L-arginine (L-Arg) ameliorate intestinal inflammation, however the exact mechanisms of this effect are unclear. We hypothesized the anti-inflammatory effects of L-Arg require active transport and metabolism by inducible
Qinghe Meng +3 more
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Use of membrane vesicles to estimate the numbers of system y+ and system L amino acid transporters in human erythrocytes [PDF]
Biochemical Journal, 1991 We have used equilibrium values for L-leucine and L-lysine uptake by right-side-out vesicles to estimate the membrane abundance (sites/cell) of Na(+)-dependent amino acid transport systems L and y+ in human erythrocytes. All of the intravesicular space was accessible to L-leucine, as judged by comparisons with uridine uptake via the equilibrative ...
C M, Tse +3 more
openaire +2 more sources
JMIR Research Protocols, 2023 BackgroundFatigue is a strong predictor of negative health outcomes in older adults. Kynurenine, a metabolite of tryptophan, is strongly associated with fatigue.
Ronna N Robbins +4 more
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SLC7A7 is a prognostic biomarker correlated with immune infiltrates in non-small cell lung cancer
Cancer Cell International, 2021 Background SLC7A7 (solute carrier family 7, amino acid transporter light chain, y + L system, member 7) is a critical gene in the regulation of cationic amino acid transport.
Wumin Dai +7 more
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Transport of Amino Acids Across the Blood-Brain Barrier
Frontiers in Physiology, 2020 The blood-brain-barrier (BBB), present in brain capillaries, constitutes an essential barrier mechanism for normal functioning and development of the brain.
Rosa Zaragozá
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