Results 211 to 220 of about 68,125 (243)
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Branched-Chain Amino Acid Metabolism
Annual Review of Nutrition, 1984INTRODUCTION . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1 0 METABOLISM O F BRANCHED·CHAIN AMINO ACIDS (BCAA) AND BRANCHED·CHAIN Q·KETOACIDS (BCKA) . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . .
A E, Harper, R H, Miller, K P, Block
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2016
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. They are also valued as synthetic intermediates for pharmaceuticals.
Keisuke, Yamamoto +2 more
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Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. They are also valued as synthetic intermediates for pharmaceuticals.
Keisuke, Yamamoto +2 more
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2007
The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are synthesized by bacteria, fungi, and plants, but are essential for vertebrates including humans, who must receive them from their diet. The interest to construct overproducing industrial strains therefore stems from the need to supplement the food or feed with these amino acids ...
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The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are synthesized by bacteria, fungi, and plants, but are essential for vertebrates including humans, who must receive them from their diet. The interest to construct overproducing industrial strains therefore stems from the need to supplement the food or feed with these amino acids ...
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Branched-chain amino acids in disease
Science, 2019Are BCAAs a biomarker, causal agent, or both in cardiometabolic disease?
Phillip J, White, Christopher B, Newgard
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Branched-chain amino acids in cardiovascular disease
Nature Reviews Cardiology, 2022Research conducted in the past 15 years has yielded crucial insights that are reshaping our understanding of the systems physiology of branched-chain amino acid (BCAA) metabolism and the molecular mechanisms underlying the close relationship between BCAA homeostasis and cardiovascular health. The rapidly evolving literature paints a complex picture, in
Robert W. McGarrah, Phillip J. White
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Current Opinion in Clinical Nutrition and Metabolic Care, 2013
There is burgeoning evidence that branch chain amino acids (BCAAs) are biomarkers of metabolic, cardiovascular, renal and cerebrovascular disease. The purpose of this review is to summarize the current evidence in this area.Recent evidence demonstrates that BCAAs are associated with insulin resistance, type 2 diabetes, risk of cardiovascular disease ...
Bryan C, Batch +2 more
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There is burgeoning evidence that branch chain amino acids (BCAAs) are biomarkers of metabolic, cardiovascular, renal and cerebrovascular disease. The purpose of this review is to summarize the current evidence in this area.Recent evidence demonstrates that BCAAs are associated with insulin resistance, type 2 diabetes, risk of cardiovascular disease ...
Bryan C, Batch +2 more
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Hepatology Research, 2004
Significant evidence of the pharmacological and physiological effects of branched-chain amino acids (BCAA) has accumulated, attracting the interest of not only clinicians but also basic medical researchers. We summarize here the characteristic features of BCAA catabolism, focusing on the initial two enzymes in the pathway, branched-chain ...
Yoshiharu, Shimomura +7 more
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Significant evidence of the pharmacological and physiological effects of branched-chain amino acids (BCAA) has accumulated, attracting the interest of not only clinicians but also basic medical researchers. We summarize here the characteristic features of BCAA catabolism, focusing on the initial two enzymes in the pathway, branched-chain ...
Yoshiharu, Shimomura +7 more
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Regulation of Branched-Chain Amino Acid Catabolism ,
The Journal of Nutrition, 1994Catabolism of the branched-chain amino acids is regulated in part at the step catalyzed by the branched-chain alpha-ketoacid dehydrogenase complex. Previous work suggests both short-term and long-term control mechanisms are involved in regulation of the kinase responsible for phosphorylation and inactivation of the branched-chain alpha-ketoacid ...
R A, Harris +3 more
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Branched Chain Amino Acids in Metabolic Disease
Current Diabetes Reports, 2018Elevations in circulating branched chain amino acids (BCAAs) have gained attention as potential contributors to the development of insulin resistance and diabetes.Epidemiological evidence strongly supports this conclusion. Suppression of BCAA catabolism in adipose and hepatic tissues appears to be the primary drivers of plasma BCAA elevations.
Zoltan, Arany, Michael, Neinast
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