Results 121 to 130 of about 145,462 (315)
Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity
Journal of Neuroscience, 2018 Ototoxic side effects of cisplatin and aminoglycosides have been extensively studied, but no therapy is available to date. Sensory hair cells, upon exposure to cisplatin or aminoglycosides, undergo apoptotic and necrotic cell death.
D. Ruhl +10 more
semanticscholar +1 more source
Walla Walla General Hospital: Setting Staff Up for Success in Pneumonia Care [PDF]
, 2010 Outlines education and reinforcement strategies, including building a quality culture and implementing a hospitalist program, standardized order sets, and staff supports, that enable high performance on pneumonia care core measures.
Aimee Lashbrook
core
Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment [PDF]
, 2009 The rapid detection of Mycobacterium tuberculosis isolates resistant to second-line drugs is crucial for the institution of appropriate treatment regimens as early as possible.
Feuerriegel, S +6 more
core +2 more sources
Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm
Macromolecular Rapid Communications, EarlyView.Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz +4 more
wiley +1 more source
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Kaohsiung Journal of Medical Sciences, 2017 Today Methicillin‐Resistant Staphylococcus aureus (MRSA) have acquired multiple resistance to a wide range of antibiotics including aminoglycosides.
A. Khosravi, Atefeh Jenabi, E. Montazeri
semanticscholar +1 more source
Bifidobacterial Dominance of the Gut in Early Life and Acquisition of Antimicrobial Resistance. [PDF]
, 2018 Bifidobacterium species are important commensals capable of dominating the infant gut microbiome, in part by producing acids that suppress growth of other taxa.
Ahmad, SM +7 more
core +1 more source
Responsive Materials, EarlyView.An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma +8 more
wiley +1 more source
Aminoglycosides: Nephrotoxicity [PDF]
Antimicrobial Agents and Chemotherapy, 1999 Mingeot-Leclercq, Marie-Paule +1 more
openaire +3 more sources
Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions
Sensory Neuroscience, EarlyView.ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang +7 more
wiley +1 more source