Results 111 to 120 of about 145,462 (315)

Aminoglycoside Heteroresistance in Acinetobacter baumannii AB5075

Msphere, 2018
Acinetobacter baumannii has become an important pathogen in hospitals worldwide, where the incidence of these infections has been increasing. A. baumannii infections have become exceedingly difficult to treat due to a rapid increase in the frequency of ...
S. Anderson, Edgar X. Sherman, D. Weiss, P. Rather   +3 more
semanticscholar   +1 more source

Optimizing Guideline-Recommended Antibiotic Doses for Pediatric Infective Endocarditis [PDF]

, 2016
The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. The recommendations included for vancomycin, aminoglycoside, and β-lactam dosing and monitoring are based ...
Israel, Emily N., Knoderer, Chad A., Nichols, Kristen R., Thomas, Christopher A.   +3 more
core   +3 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Towards the Prevention of Aminoglycoside-Related Hearing Loss

Frontiers in Cellular Neuroscience, 2017
Aminoglycosides are potent antibiotics deployed worldwide despite their known side-effect of sensorineural hearing loss. The main etiology of this sensory deficit is death of inner ear sensory hair cells selectively triggered by aminoglycosides.
M. O'Sullivan, A. Pérez, R. Lin, Autefeh Sajjadi, A. Ricci, A. Cheng   +5 more
semanticscholar   +1 more source

Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements [PDF]

, 2014
INTRODUCTION: Infections caused by Acinetobacter junii are rarely reported. However, some outbreaks of septicemia in neonates and pediatric oncology patients, as well as meningitis, peritonitis, and ocular infection have been described.
Almuzara, Marisa, Centron, Daniela, Neumann, Gabriela, Pallone, Elida Carmen, Ramirez, Maria Soledad, Traglia, German Matias, Tuduri, Alicia, Vilacoba, Elisabet   +7 more
core   +1 more source

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Berbamine Analogs Exhibit Differential Protective Effects From Aminoglycoside-Induced Hair Cell Death

Frontiers in Cellular Neuroscience, 2020
Hearing loss is the third most common chronic health condition in the United States and largely results from damage to sensory hair cells. Major causes of hair cell damage include aging, noise exposure, and medications such as aminoglycoside antibiotics.
Alexandria M. Hudson, Gavin M. Lockard, Ojas A. Namjoshi, Joseph W. Wilson, Katie S. Kindt, Bruce E. Blough, Allison B. Coffin, Allison B. Coffin   +7 more
doaj   +1 more source

Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]

, 2010
Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core   +2 more sources

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Contribution of RaeB, a Putative RND-Type Transporter to Aminoglycoside and Detergent Resistance in Riemerella anatipestifer

Frontiers in Microbiology, 2017
Riemerella anatipestifer is an important pathogenic bacterium that infects ducks. It exhibits resistance to multiple classes of antibiotics. Multidrug efflux pumps play a major role as a mechanism of antimicrobial resistance in Gram-negative pathogens ...
Xin Zhang, Xin Zhang, Xin Zhang, Ming-Shu Wang, Ming-Shu Wang, Ming-Shu Wang, Ma-Feng Liu, Ma-Feng Liu, Ma-Feng Liu, De-Kang Zhu, De-Kang Zhu, De-Kang Zhu, Francis Biville, Ren-Yong Jia, Ren-Yong Jia, Ren-Yong Jia, Shun Chen, Shun Chen, Shun Chen, Kun-Feng Sun, Kun-Feng Sun, Kun-Feng Sun, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Xin-Xin Zhao, Xin-Xin Zhao, Xin-Xin Zhao, Xiao-Yue Chen, An-Chun Cheng, An-Chun Cheng, An-Chun Cheng   +34 more
doaj   +1 more source