Results 21 to 30 of about 93,718 (253)
bioRxiv, 2019 Stop codon readthrough (SCR) occurs when the ribosome miscodes at a stop codon. Such readthrough events can be therapeutically desirable when a premature termination codon (PTC) is found in a critical gene.
J. Wangen, R. Green
semanticscholar +1 more source
Sustained Neuromuscular Blockade after Vecuronium Use in a Premature Infant
American Journal of Perinatology Reports, 2015 Background Prolonged use of neuromuscular blocking agents (NMBAs) is very common in critically ill children both in pediatric and neonatal intensive care units. There are no guidelines available for use of NMBAs in children or neonates in the US, and the
Mitali Sahni +2 more
doaj +1 more source
Frontiers in Neurology, 2021 Background: Patients with vestibular schwannoma that show residual peripheral-vestibular function before surgery may experience sudden and substantial vestibular loss of function after surgical resection.
Alexander A. Tarnutzer +15 more
doaj +1 more source
RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa
Emerging Infectious Diseases, 2015 We investigated 16S rRNA methyltransferases in 38 blaNDM-1–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF.
Mohibur Rahman +7 more
doaj +1 more source
Biosensors, 2019 On-site therapeutic drug monitoring (TDM) is important for providing a quick and accurate dosing to patients in order to improve efficacy and minimize toxicity.
Zaidon T. Al-aqbi +3 more
doaj +1 more source
Antimicrobial Synergy between Aminoglycosides and Licorice Extract in Listeria monocytogenes
Pathogens, 2022 Listeria monocytogenes is a foodborne pathogen that can develop serious invasive infections. Among foodborne pathogens, L. monocytogenes exhibits the highest case fatality despite antibiotic treatment, suggesting the current therapy should be improved ...
Myungseo Park +5 more
doaj +1 more source
Aminoglycosides: Time for the Resurrection of a Neglected Class of Antibacterials?
ACS Infectious Diseases, 2019 This Viewpoint addresses the question of whether, after years of declining use, the time is ripe for renewed investigations into the aminoglycoside class of antibiotics for the development of novel therapeutic agents for the treatment of drug-resistant ...
E. Böttger, D. Crich
semanticscholar +1 more source
Aminoglycosides and kidney function [PDF]
Journal of Medical Biochemistry, 2007 The aminoglycosides are bactericide antibiotics with predominant effecting on the Gramm-negative bacterias, then staphylococci and mycobacteria with a small therapeutic range and with expressive ototoxic, nephrotoxic and with rare neurotoxic side effects.
Stanić Momčilo +2 more
doaj
Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility
mBio, 2023 Aminoglycosides (AG) have been used against Gram-negative bacteria for decades. Yet, how bacterial metabolism and environmental conditions modify AG toxicity is poorly understood.
Jessica Y. El Khoury +4 more
doaj +1 more source
Kidney International, 1980 Nephrotoxicity has been recognized as a major complication of aminoglycoside antibiotics for many years. During the past 6 to 8 years, this problem has attracted the attention and interest of a number of investigators, resulting in the generation of a large body of experimental data that has greatly expanded our understanding of the pathogenesis of ...
Kaloyanides, George J. +1 more
openaire +2 more sources